Metabolite details
Reactome pathways
- R-HSA-110329 - Cleavage of the damaged pyrimidine
- R-HSA-1430728 - Metabolism
- R-HSA-15869 - Metabolism of nucleotides
- R-HSA-382551 - Transport of small molecules
- R-HSA-425397 - Transport of vitamins, nucleosides, and related molecules
- R-HSA-425407 - SLC-mediated transmembrane transport
- R-HSA-73614 - Pyrimidine salvage
- R-HSA-73621 - Pyrimidine catabolism
- R-HSA-73884 - Base Excision Repair
- R-HSA-73894 - DNA Repair
- R-HSA-73928 - Depyrimidination
- R-HSA-73929 - Base-Excision Repair, AP Site Formation
- R-HSA-83936 - Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
- R-HSA-8956319 - Nucleotide catabolism
- R-HSA-8956321 - Nucleotide salvage
Observed in studies
- Biological effect of chronic mistranslation in mammalian cells
- Absence of tmRNA Increases the Persistence to Cefotaxime and the Intercellular Accumulation of Metabolite GlcNAc in <i>Aeromonas veronii</i>.
- Absence of tmRNA increases the persistence to cefotaxime by upregulating the metabolites GlcNAc in Aeromonas veronii
- New insights into the responses of soil microorganisms to polycyclic aromatic hydrocarbon stress by combining enzyme activity and sequencing analysis with metabolomics.
- Distribution of RESV and its metabolite peaks in mouse tissues after oral and skin administration
- Resveratrol metabolism in HepG2 (human hepatocytes), HaCaT (human keratinocytes), and C2C12 (mouse myoblasts)
- Cell-based and multi-omics profiling reveal dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei
- Hfq Regulates Efflux Pump Expression and Purine Metabolic Pathway to Increase the Trimethoprim Resistance in Aeromonas veronii
- Metabolomic Profile of Diet-Induced Obesity Mice in Response to Human and Small Humanin-like Peptide 2 Treatment
- Unknown Metabolite Annotation in Mouse Aging using Ion Mobility Collision Cross-Section Atlas (AllCCS)
- A metabolite roadmap of the wood-forming tissue in Populus tremula (GC-MS assay; Wood ring and extraxylary tissue)
- How Does the Seed Pre-germinative Metabolism Fight against Imbibition Damage; Emerging Roles of Fatty Acid Cohort and Antioxidant Defence
- Metabolic cooperation and spatiotemporal niche partitioning in a kefir microbial community; Interaction between the kefir isolates Lactococcus lactis and Acetobacter fabarum (GC-MS)
- The impact of slyA on cell metabolism of Salmonella Typhimurium: a joint study of transcriptomics and
- Fruit setting rewires central metabolism via gibberellin cascades
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Escherichia coli assays)
- Metabolic Dynamics of In Vitro CD8+ T Cell Activation.
- Metabolomic profiling reveals the effects of early-life lactoferrin intervention on protein synthesis, energy production and antioxidative capacity in the liver of suckling piglets
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Klebsiella pneumoniae assays)
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Streptococcus pneumoniae assays)
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Streptococcus pyogenes assays)
- Multi-Omics Analysis Reveals Disturbance of Nanosecond Pulsed Electric Field in the Serum Metabolic Spectrum and Gut Microbiota
- Transcriptional differentiation of Trypanosoma brucei during in vitro acquisition of resistance to acoziborole
- Metabolic Dynamics in <i>Escherichia coli</i>-Based Cell-Free Systems
- Efficacy of Zhuyu Pill Intervention in a Cholestasis Rat Model: Mutual Effects on Fecal Metabolism and Microbial Diversity
- Fat Deposition in the Muscle of Female and Male Yak and the Correlation of Yak Meat Quality with Fat
- Transcriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth
- Metabolites from surface seawater collected in Narragansett Bay
- A Phosphate starvation response gene (psr1-like) is present in Micromonas pusilla and other marine algae and coordinates the metabolic response to phosphate deficiency
- Multiomics of tomato glandular trichomes reveals distinct features of central carbon metabolism supporting high productivity of specialized metabolites
- Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 21)
- Metabolomics dataset of PPAR-pan treated rat liver (acyl-carnitine and aqueous metabolite assays)
- Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 10)
- Jasmonate-mediated stomatal closure under elevated CO2 revealed by time-resolved metabolomics
- Multiple biochemical indices and metabolomics of Clonorchis sinensis provide a novel interpretation of biomarkers
- Chronic sleep loss sensitizes Drosophila melanogaster to nitrogen stress
- Metabolomics Analysis of the Effect of GAT-2 Deficiency on Th1 Cells in Mice
- Analysis of Growth Phases of Enterotoxigenic Escherichia coli Reveals a Distinct Transition Phase before Entry into Early Stationary Phase with Shifts in Tryptophan, Fucose, and Putrescine Metabolism and Degradation of Neurotransmitter Precursors
- Metabolomic analysis of the mechanism of action of yerba mate extract on Salmonella Typhimurium
- Metabolomics and lipidomics reveal perturbation of sphingolipid metabolism by a novel anti-trypanosomal 3-(oxazolo[4,5-b]pyridine-2-yl)anilide
- Metabolic plasticity confers increased resilience to climate variability in temperate compared to tropical lizards
- Distinct succinate modifying products are clinically diagnostic and prognostic biomarkers for fumarate hydratase deficient renal cell carcinoma
- Gut microbiome drives individual memory variation in bumblebees
- The Manchurian Walnut Genome: Insights into Juglone and Lipid Biosynthesis.
- Diallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice
- Appropriate taxonomic classification of intestinal microbiome by 16S rRNA gene targeting metagenomic approach
- Metabolism Disorder Promotes Isoproterenol-induced Myocardial Injury in Mice with High Temperature and High Humidity and High-Fat Diet
- Exercise-generated β-aminoisobutyric acid (BAIBA) reduces cardiomyocytes metabolic stress and apoptosis caused by mitochondrial dysfunction through the miR-208b/AMPK pathway
- Metabolic profilings of rat INS-1 β-cells under changing levels of essential amino acids
- Unbiased characterization of genotype-dependent metabolic regulations by metabolomic approach in Arabidopsis thaliana
- Transcriptome and Metabolome Analyses Reveal Differences in Terpenoid and Flavonoid Biosynthesis in Cryptomeria fortunei Needles Across Different Seasons
- Effects of Radiofrequency Field from 5G Communications on fecal microbiome and metabolome profiles in mice
- Homeostasis of the biosynthetic E. coli metabolome
- Mining for metabolic responses to long-term salt stress: a case study on the model legume Lotus japonicus (A)
- Comparative Analysis of Host Metabolic Alterations in Murine Malaria Models with Uncomplicated or Severe Malaria
- Mining for metabolic responses to long-term salt stress: a case study on the model legume Lotus japonicus (B)
- Auricularia auricula polysaccharides reduce obesity in mice through gut commensal Papillibacter cinnamivorans
- Integrated metabolomics and transcriptome revealed the effect of fermented Lycium barbarum residue promoting Ovis aries immunity
- Cardiac disruption of SDHAF4-mediated mitochondrial complex II assembly promotes dilated cardiomyopathy.
- Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors
- Integrated Metabolomics and Transcriptomics Analyses Reveal Anthocyanin and Carotenoid Biosynthesis Involved in Color Development in Willow Bark
- Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Feces metabolomics)
- Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Brain tissue metabolomics)
- Sodium Butyrate mediates Histone Crotonylation and Alleviated Neonatal Rats Hypoxic-Ischemic Brain Injury Through Gut-Brain Axis (untargeted fecal metabolomics)
- Mechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis
- Multiomic analysis revealed the potential role of rumen microbes in heat stress
- Effect of heat stress on serum enzyme activity, antioxidant capacity and immune parameter metabolomics datasets in Holstein cows at different growth stages
- Stage-specific roles of microbial dysbiosis and metabolic disorders in rheumatoid arthritis
- PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis.
- Alterations in the gut microbiota and metabolomics of seafarers after a six-month sea voyage
- Bile acid is a significant host factor shaping the gut microbiome of diet induced obese mice (untargeted metabolome profile assay)
- Integrated Proteomic and Metabolomic Analyses Show Differential Effects of Glucose Availability in Marine <i>Synechococcus</i> and <i>Prochlorococcus</i>.
- Metabolic disorder and intestinal microflora dysbiosis in chronic inflammatory demyelinating polyradiculoneuropathy
- Transcriptomic and lipidomic profiling of subcutaneous and visceral adipose tissues in 15 vertebrates
- DNA-PKcs drives CKD progression by activating TAF7/RAPTOR/mTORC1 signaling-mediated metabolic reprogramming
- Transcriptomics and metabolomics analysis reveal the anti-oxidation and immune boosting effects of mulberry leaves in growing mutton sheep
- A Pilot Characterization of the Human Chronobiome
- Comparative metabolomic analysis of exudates of microcystin-producing and microcystin-free Microcystis aeruginosa strains
- Extracellular-acidosis restricts one-carbon metabolism and preserves T cell stemness
- Metabolic changes associated with tick-microbe interactions
- TGF-β uncouples glycolysis and inflammation in macrophages and controls the survival during sepsis
- Unraveling the metabolic effects of benzophenone-3 on the endosymbiotic dinoflagellate Cladocopium goreaui
- Genetic mapping and molecular mechanism behind color variation in the Asian vine snake
- Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice
- Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction
- Disturbed Microbiota-Metabolites-Immune Interaction Network is Associated with Olfactory Dysfunction in Patients with Chronic Rhinosinusitis
- L-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS positive mode)
- L-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS negative mode)
- Metabolic effects of an aspartate aminotransferase-inhibitor on two T-cell lines
- Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency.
- Unexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites (Blood fraction)
- Searching for Drug Synergy Against Cancer Through Polyamine Metabolism Impairment: Insight Into the Metabolic Effect of Indomethacin on Lung Cancer Cells.
- Unexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites (Blood plasma and RBC fractions)
- Decreased abundance of type III secretion systeminducing signals in Arabidopsis mkp1 enhances resistance against Pseudomonas syringae
Observed in differential profiles
- rps2_wildtype_vs_rps2_A226Y
- Wild_Type_vs_tmRNA_Deletion
- Wild_Type_vs_tmRNA_Knockout
- Wild_Type_vs_tmRNA_Knockout
- Low_Contamination_vs_High_Contamination
- Control_Oral_Blood_vs_RESV_Oral_Blood
- Control_Oral_Blood_vs_RESV_Oral_Blood
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- Non_Induced_0_Day_vs_Induced_8_Day
- Non_Induced_0_Day_vs_Induced_8_Day
- Wild_type_vs_hfq
- Wild_type_vs_hfq
- Water_vs_HNG
- Water_vs_HNG
- Water_vs_HNG
- Water_vs_HNG
- 36_week_vs_104_week
- Phloem_vs_Cambium
- Dry_Seed_vs_8h_Imbibed_Seed
- Milk_0h_vs_Whey_72h
- slyA_vs_wild_type
- G1_Wild_Type_Day_-2_Pollination_0_vs_G3_Wild_Type_Day_2_Pollination_1
- RPMI_B36_vs_Pooled_Sera_B36
- RPMI_B36_vs_Pooled_Sera_B36
- G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
- G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
- Control_Day_8_vs_Lactoferrin_Day_8
- G1_Klebsiella_pneumoniae_AJ218_RPMI_vs_G2_Klebsiella_pneumoniae_AJ218_Pooled_sera
- G1_Pooled_Sera_Blood_4559_vs_G2_RPMI_Glucose_Blood_4559
- G1_Pooled_Sera_Blood_4559_vs_G2_RPMI_Glucose_Blood_4559
- G1_RPMI_modified_Blood_M1T1_5448_vs_G2_Pooled_sera_Blood_M1T1_5448
- G1_RPMI_modified_Blood_M1T1_5448_vs_G2_Pooled_sera_Blood_M1T1_5448
- Control_vs_nsPEF_7_day
- WT_vs_WT_Aco
- G1_Exp1_0_hours_vs_G2_Exp1_6_hours
- Control_vs_CF_high
- Male_vs_Female
- Wild_Type_vs_YQ2-gal
- 16_May_2012_vs_8_June_2012
- 16_May_2012_vs_8_June_2012
- Intracellular_vs_Extracellular
- Intracellular_vs_Extracellular
- Solanum_habrochaites_leaf_vs_glandular_trichome
- Sham_vs_UIR
- Control_vs_High
- Sham_vs_UIR
- 400ppm_0min_vs_800ppm_60min
- Control_14dpi_vs_Infected_14dpi
- Control_14dpi_vs_Infected_14dpi
- Iso31_Control_vs_Fumin_Homozygous_Sleep_Mutants
- GAT-2_Knockout_vs_Wild_Type
- E1777_Intracellular_MidLog_vs_E1777_Intracellular_EarlyStationary
- No_Tea_0min_vs_Tea_240min
- Control_vs_OXPA_Treatment
- Control_vs_OXPA_Treatment
- T_septentrionalis_cold_vs_T_septentrionalis_warm
- Normal_control_no_tumor_vs_FH_deficient_RCC
- Hindgut_Control_vs_Lactobacillus_apis
- Embryo_S1_vs_Embryo_S4
- G1_PBS_vs_G2_DSS
- Untreated_vs_Antibiotic_Treated
- Untreated_vs_Antibiotic_Treated
- Control_vs_Isoproterenol
- Sham_vs_Heart_Failure_Sedentary
- Sham_vs_Heart_Failure_Sedentary
- G1_Control_vs_G2_Arginine_Addition
- Summer_vs_Winter
- Col-0_vs_tt4
- Sham_vs_Radiofrequency
- Glu_BW25113_vs_Pyr_BW25113
- Uninfected_BALB/c_vs_Plasmodium_yoelii_17XL_BALB/c
- Control_vs_150mM
- Basal_vs_High_Fat
- Control_vs_150mM
- RCON_vs_RFW
- Wild_type_vs_Knock_out
- Wild_Type_vs_Gene_Knockout
- Purple_vs_Green
- Normal_vs_Neural_Tube_Defect
- Normal_vs_Neural_Tube_Defect
- Normal_vs_Neural_Tube_Defect
- Sham_vs_HIBD
- Control_vs_ZYP_High_Dose
- Dc-N_vs_Dc-HS
- Dcs_N_vs_Dcs_HS
- Healthy_vs_RAS4
- Control_0d_vs_Treatment_180d
- MCF-7_WT_vs_MCF-7_PKM2_KO
- Normal_Diet_vs_High-fat_Diet
- Normal_Diet_vs_High-fat_Diet
- Normal_Diet_vs_High-fat_Diet
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- CIDP_patient_vs_healthy_control
- G1_Sheep_ASA_SAT_vs_G2_Sheep_GOM_VAT
- DNA-PK_KO_UUO_vs_DNA-PK_KO_Control
- Control_vs_Fermented_Mulberry_Leaves
- Plasma_0h_vs_Plasma_48h
- MC-producing_Exponential_vs_MC-free_Exponential
- Control_vs_Lactic_Acid
- Uninfected_1h_vs_Anaplasma_phagocytophilum_1h
- Control_vs_TGF-beta_Treatment
- Control_vs_BP3_Low_Concentration
- Yellow_Skin_vs_Green_Skin
- ASD_Fecal_vs_TD_Fecal
- Arginine_Replenished_Ctrl_vs_Arginine_Starved_48h
- Normal_vs_Abnormal
- Normal_vs_Abnormal
- SAR-S_vs_SAR-R
- SAR-R_vs_SAR-S
- JURKAT_Control_vs_JURKAT_Treatment
- WT_vs_ErbB2_KI
- A549_0uM_vs_A549_1uM
- Human_Blood_vs_Human_Plasma
- Human_Blood_vs_Human_Plasma
- Human_Blood_vs_Human_Plasma
- Blood_vs_Plasma
- Blood_vs_Plasma
- WT_vs_MPK1_Mutant