Diff Profiles › MTBLS873_0001_00000002

A549_0uM_vs_A549_1uM

A549_0uM vs A549_1uM

p-value ≤ 0.05 17 significant 2025-09-26 00:00:00 Study: MTBLS873
112 Total Features
17 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS873_0001_00000002
Linked study
MTBLS873 — Searching for Drug Synergy Against Cancer Through Polyamine Metabolism Impairment: Insight Into the Metabolic Effect of Indomethacin on Lung Cancer Cells.
Comparison
A549_0uM vs A549_1uM
Group A
A549 cell line with 0 micromolar indomethacin dose. Provides baseline for comparison with treated A549 samples.
Group B
A549 cell line with 1 micromolar indomethacin dose. Allows assessment of high-dose indomethacin effects on A549 cells.
Total features tested
112
Significant features
17
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
SUHOOTKUPISOBE-UHFFFAOYSA-N colamine phosphate down 0.03549 7.91e-06
FFEARJCKVFRZRR-BYPYZUCNSA-N L-Methionine down 0.09574 0.00108
ROHFNLRQFUQHCH-YFKPBYRVSA-N <small>L</small>-Leuzin down 0.06423 0.00787
JVGVDSSUAVXRDY-UHFFFAOYSA-N 2-Hydroxy-3-(4-hydroxyphenyl)propanoate down 0.1786 0.00357
OWBTYPJTUOEWEK-UHFFFAOYSA-N 2,3-Dihydroxybutane down 0.1726 0.0141
VZCYOOQTPOCHFL-OWOJBTEDSA-N (2<i>E</i>)-2-butenedioic acid down 0.244 0.00585
FBPFZTCFMRRESA-UNTFVMJOSA-N <small>L</small>-Idit down 0.2692 0.00405
QEFRNWWLZKMPFJ-YGVKFDHGSA-N <small>L</small>-methionine sulfoxide down 0.2132 0.0131
DEFJQIDDEAULHB-IMJSIDKUSA-N <small>L</small>-Ala-<small>L</small>-Ala down 0.2126 0.0153
ILRYLPWNYFXEMH-WHFBIAKZSA-N S-(beta-amino-beta-carboxyethyl)homocysteine down 0.2433 0.015