{"@type":"Dataset","go_id":["https://identifiers.org/GO:0000050","https://identifiers.org/GO:0006596","https://identifiers.org/GO:0006595"],"go_kw":["urea cycle","polyamine synthesis","polyamine metabolism"],"integmet_study":"MTBLS873","mesh_chemical_id":["https://identifiers.org/mesh:D011073","https://identifiers.org/mesh:D007213","https://identifiers.org/mesh:D000518","https://identifiers.org/mesh:D011700","https://identifiers.org/mesh:C044445","https://identifiers.org/mesh:D009952","https://identifiers.org/mesh:D013095","https://identifiers.org/mesh:D013096","https://identifiers.org/mesh:D008715","https://identifiers.org/mesh:D014508"],"mesh_chemical_pubtator_kw":["polyamines","indomethacin","eflornithine","polyamine","putrescine","MDL72527","ornithine","spermidine","Polyamine","Indomethacin","spermine","methionine","urea"],"mesh_disease_id":["https://identifiers.org/mesh:D008175","https://identifiers.org/mesh:D002289","https://identifiers.org/mesh:D007249","https://identifiers.org/mesh:D009369"],"mesh_disease_pubtator_kw":["Lung Cancer","NSCLC","inflammatory","cancer","Cancer","tumor","Non-small cell lung cancer","lung cancer"],"mesh_gene_id":["https://identifiers.org/ncbigene:4953","https://identifiers.org/ncbigene:6303","https://identifiers.org/ncbigene:54498","https://identifiers.org/ncbigene:196743"],"mesh_gene_pubtator_kw":["ornithine decarboxylase","spermidine/spermine-N1-acetyltransferase","spermine oxidase","polyamine oxidase","SAT1","SSAT"],"source_id":"https://identifiers.org/metabolights:MTBLS873","study_findings":"Indomethacin alters polyamine metabolism and enhances polyamine synthesis inhibitors' effects in NSCLC cells.","study_observation":"Effect of indomethacin on NSCLC cell lines A549 and H1299.","study_summary":"Indomethacin affects polyamine metabolism in NSCLC cells.","study_title_original":"Searching for Drug Synergy Against Cancer Through Polyamine Metabolism Impairment: Insight Into the Metabolic Effect of Indomethacin on Lung Cancer Cells."}