{"comparisonGroups":["A549_0uM","A549_1uM"],"dateCreated":"2025-09-26 00:00:00","display_title":"A549 cells: 1\u03bcM vs 0\u03bcM indomethacin treatment","group_a_title":"A549 cell line with 0 micromolar indomethacin dose. Provides baseline for comparison with treated A549 samples.","group_b_title":"A549 cell line with 1 micromolar indomethacin dose. Allows assessment of high-dose indomethacin effects on A549 cells.","id":"MTBLS873_0001_00000002","pvalueThreshold":0.05,"ratioThresholdLower":"1/1.5","ratioThresholdUpper":1.5,"significantFeatures":17,"studyId":"MTBLS873","studyUrl":"http://integmet.org/study/MTBLS873","title":"A549_0uM_vs_A549_1uM","topHits":[{"chebi_id":"17553","direction":"down","inn_name":"","iupac_name":"2-aminoethyl dihydrogen phosphate","metabolite_id":"SUHOOTKUPISOBE-UHFFFAOYSA-N","pvalue":7.910734144660452e-06,"ratio":0.0354938017943365,"synonym_name":"colamine phosphate"},{"chebi_id":"16643","direction":"down","inn_name":"","iupac_name":"<small>L</small>-methionine","metabolite_id":"FFEARJCKVFRZRR-BYPYZUCNSA-N","pvalue":0.0010793592197543,"ratio":0.0957408822459599,"synonym_name":"L-Methionine"},{"chebi_id":"15603","direction":"down","inn_name":"","iupac_name":"<small>L</small>-leucine","metabolite_id":"ROHFNLRQFUQHCH-YFKPBYRVSA-N","pvalue":0.0078735036672876,"ratio":0.0642338136217061,"synonym_name":"<small>L</small>-Leuzin"},{"chebi_id":"17385","direction":"down","inn_name":"","iupac_name":"2-hydroxy-3-(4-hydroxyphenyl)propanoic acid","metabolite_id":"JVGVDSSUAVXRDY-UHFFFAOYSA-N","pvalue":0.0035747029062845,"ratio":0.1786198864327529,"synonym_name":"2-Hydroxy-3-(4-hydroxyphenyl)propanoate"},{"chebi_id":"62064","direction":"down","inn_name":"","iupac_name":"butane-2,3-diol","metabolite_id":"OWBTYPJTUOEWEK-UHFFFAOYSA-N","pvalue":0.0141409971494183,"ratio":0.172627527769218,"synonym_name":"2,3-Dihydroxybutane"},{"chebi_id":"18012","direction":"down","inn_name":"","iupac_name":"(2<i>E</i>)-but-2-enedioic acid","metabolite_id":"VZCYOOQTPOCHFL-OWOJBTEDSA-N","pvalue":0.0058524794032695,"ratio":0.243956254215999,"synonym_name":"(2<i>E</i>)-2-butenedioic acid"},{"chebi_id":"18202","direction":"down","inn_name":"","iupac_name":"<small>L</small>-iditol","metabolite_id":"FBPFZTCFMRRESA-UNTFVMJOSA-N","pvalue":0.0040525887072257,"ratio":0.269226525126553,"synonym_name":"<small>L</small>-Idit"},{"chebi_id":"17016","direction":"down","inn_name":"","iupac_name":"<small>L</small>-methionine <em>S</em>-oxide","metabolite_id":"QEFRNWWLZKMPFJ-YGVKFDHGSA-N","pvalue":0.0130546548359711,"ratio":0.2132247571584408,"synonym_name":"<small>L</small>-methionine sulfoxide"},{"chebi_id":"72816","direction":"down","inn_name":"","iupac_name":"<small>L</small>-alanyl-<small>L</small>-alanine","metabolite_id":"DEFJQIDDEAULHB-IMJSIDKUSA-N","pvalue":0.0152930242771247,"ratio":0.2126470174137552,"synonym_name":"<small>L</small>-Ala-<small>L</small>-Ala"},{"chebi_id":"17482","direction":"down","inn_name":"","iupac_name":"<small>L</small>-cystathionine","metabolite_id":"ILRYLPWNYFXEMH-WHFBIAKZSA-N","pvalue":0.0150034501239703,"ratio":0.2433491573982888,"synonym_name":"S-(beta-amino-beta-carboxyethyl)homocysteine"}],"totalFeatures":112}