Diff Profiles › MTBLS360_0001_00000001

Control_vs_OXPA_Treatment

Control vs OXPA_Treatment

p-value ≤ 0.05 14 significant 2025-09-26 00:00:00 Study: MTBLS360
503 Total Features
14 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS360_0001_00000001
Linked study
MTBLS360 — Metabolomics and lipidomics reveal perturbation of sphingolipid metabolism by a novel anti-trypanosomal 3-(oxazolo[4,5-b]pyridine-2-yl)anilide
Comparison
Control vs OXPA_Treatment
Group A
Control samples without OXPA treatment. Provides a reference point for evaluating the effects of OXPA treatment
Group B
Samples treated with OXPA compound. Key group for assessing the efficacy of the OXPA compound against Trypanosoma brucei
Total features tested
503
Significant features
14
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
ZRVIYEJYXIDATJ-UHFFFAOYSA-N 4-Heptyloxybenzoic acid down 0.2504 0.0241
PHIQHXFUZVPYII-ZCFIWIBFSA-N L-Carnitine down 0.5047 0.00146
QBFXCLDNTKBAPQ-STSAHMJASA-N <em>N</em>-(heptadecanoyl)-hexdecasphing-4-enine up 1.949 0.00437
YDNKGFDKKRUKPY-TURZORIXSA-N <em>N</em>-(hexadecanoyl)-sphing-4-enine up 1.888 0.00369
RDHQFKQIGNGIED-UHFFFAOYSA-N Acetyl-DL-carnitine down 0.4196 0.0217
BIRSGZKFKXLSJQ-SQOUGZDYSA-N 6-Phospho-D-gluconate down 0.4434 0.0265
OBFSLMQLPNKVRW-RHPAUOISSA-N C18:1 Cer up 2.076 0.0197
ICWGMOFDULMCFL-QKSCFGQVSA-N Cer(d18:1/17:0) up 1.763 0.00857
IVBULNXGVIHEKN-MVIDNBQJSA-N N-(hexadecanoyl)-phytoceramide up 1.878 0.0199
AUNGANRZJHBGPY-SCRDCRAPSA-N E101 up 1.718 0.0135