Metabolite details
Reactome pathways
- R-HSA-1430728 - Metabolism
- R-HSA-1643685 - Disease
- R-HSA-200425 - Carnitine shuttle
- R-HSA-382551 - Transport of small molecules
- R-HSA-389887 - Beta-oxidation of pristanoyl-CoA
- R-HSA-390918 - Peroxisomal lipid metabolism
- R-HSA-425407 - SLC-mediated transmembrane transport
- R-HSA-549127 - SLC-mediated transport of organic cations
- R-HSA-556833 - Metabolism of lipids
- R-HSA-5619053 - Defective SLC22A5 causes systemic primary carnitine deficiency (CDSP)
- R-HSA-5619102 - SLC transporter disorders
- R-HSA-5619115 - Disorders of transmembrane transporters
- R-HSA-71262 - Carnitine synthesis
- R-HSA-71291 - Metabolism of amino acids and derivatives
- R-HSA-8978868 - Fatty acid metabolism
Observed in studies
- Biological effect of chronic mistranslation in mammalian cells
- Metabolome analysis via an HPLC-ESI-MS-based experimental and computational pipeline for chronic nephron toxicity profiling
- Bioaccumulation of therapeutic drugs by human gut bacteria: cross-feeding metabolite analysis (FIA-MS) (E.rectale;S.salivarius assays)
- Transcriptional differentiation of Trypanosoma brucei during in vitro acquisition of resistance to acoziborole
- Integrated Analyses of the Gut Microbiota, Intestinal Permeability and Serum Metabolome Phenotype in Rats with Alcohol Withdrawal Syndrome
- Red-Fleshed Apple Anthocyanin Extracts Attenuate Male Reproductive System Dysfunction Caused by Busulfan in Mice (Mouse blood plasma; UPLC-MS/MS assays)
- Metabolic characterization of the natural progression of chronic hepatitis B (Biogenic amine and Acyl-carnitine assays).
- Dietary carbohydrate and protein levels affect the growth performance of juvenile peanut worm (Sipunculus nudus): an LC–MS-based metabolomics study
- Changes and correlations of intestinal flora and liver metabolite profiles in mice with gallstones
- Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 21)
- Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 10)
- Analysis of Growth Phases of Enterotoxigenic Escherichia coli Reveals a Distinct Transition Phase before Entry into Early Stationary Phase with Shifts in Tryptophan, Fucose, and Putrescine Metabolism and Degradation of Neurotransmitter Precursors
- Metabolomics and lipidomics reveal perturbation of sphingolipid metabolism by a novel anti-trypanosomal 3-(oxazolo[4,5-b]pyridine-2-yl)anilide
- Distinct succinate modifying products are clinically diagnostic and prognostic biomarkers for fumarate hydratase deficient renal cell carcinoma
- Mechanical force promotes dimethylarginine dimethylaminohydrolase 1-mediated hydrolysis of the metabolite asymmetric dimethylarginine to enhance bone formation
- Diallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice
- Metabolism Disorder Promotes Isoproterenol-induced Myocardial Injury in Mice with High Temperature and High Humidity and High-Fat Diet
- Exercise-generated β-aminoisobutyric acid (BAIBA) reduces cardiomyocytes metabolic stress and apoptosis caused by mitochondrial dysfunction through the miR-208b/AMPK pathway
- Metabolic profilings of rat INS-1 β-cells under changing levels of essential amino acids
- Transcriptional Shift and Metabolic Adaptations during Leishmania Quiescence Using Stationary Phase and Drug Pressure as Models
- Novel Potential Diagnostic Serum Biomarkers of Metabolomics in Osteoarticular Tuberculosis Patients: A Preliminary Study
- Altered fecal metabolomics and potential biomarkers of psoriatic arthritis differing from rheumatoid arthritis
- Phosphoproteomic and Metabolomic Profiling Uncovers the Roles of CcPmk1 in the Pathogenicity of <i>Cytospora chrysosperma</i>
- AMPK activation orchestrated replicative senescence of periodontal ligament stem cells via regulating metabolomics
- Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors
- Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Feces metabolomics)
- Mechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis
- Stage-specific roles of microbial dysbiosis and metabolic disorders in rheumatoid arthritis
- Alterations in the gut microbiota and metabolomics of seafarers after a six-month sea voyage
- Metabolic disorder and intestinal microflora dysbiosis in chronic inflammatory demyelinating polyradiculoneuropathy
- 4-Octyl itaconate as a metabolite derivative inhibits inflammation via alkylation of STING
- Transcriptomic and lipidomic profiling of subcutaneous and visceral adipose tissues in 15 vertebrates
- GABA regulates IL-1β production in macrophages
- Extracellular-acidosis restricts one-carbon metabolism and preserves T cell stemness
- TGF-β uncouples glycolysis and inflammation in macrophages and controls the survival during sepsis
- Disturbed Microbiota-Metabolites-Immune Interaction Network is Associated with Olfactory Dysfunction in Patients with Chronic Rhinosinusitis
- L-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS positive mode)
- Plasma metabolite changes in dairy cows during parturition identified using untargeted metabolomics.
- Changing environments and genetic variation: inbreeding does not compromise short-term physiological responses
Observed in differential profiles
- rps2_wildtype_vs_rps2_A226Y
- Control_1_day_vs_High_14_day
- Control_1_day_vs_High_14_day
- G4_Eubacterium_rectale_DMSO_30_vs_G3_Eubacterium_rectale_Duloxetine_47
- WT_vs_WT_Aco
- Alcohol_Treatment_vs_Control
- Control_vs_Busulfan_5_mg_kg_RAAE
- Control_vs_Immune_Tolerant
- Control_vs_Immune_Tolerant
- Control_vs_Immune_Tolerant
- Diet_D2_vs_Diet_D5
- Control_vs_Lithogenic_Diet
- Sham_vs_UIR
- Sham_vs_UIR
- E1777_Intracellular_MidLog_vs_E1777_Intracellular_EarlyStationary
- Control_vs_OXPA_Treatment
- Control_vs_OXPA_Treatment
- Normal_control_no_tumor_vs_FH_deficient_RCC
- Control_vs_Exercise
- G1_PBS_vs_G2_DSS
- Control_vs_Isoproterenol
- Sham_vs_Heart_Failure_Sedentary
- G1_Control_vs_G2_Arginine_Addition
- AMAD_Log_vs_AMAE_Sta
- Healthy_Control_vs_Osteoarticular_Tuberculosis
- Healthy_Control_vs_Psoriatic_Arthritis
- CcPmk1_vs_Wild_type
- Passage_4_vs_Passage_20
- Wild_Type_vs_Gene_Knockout
- Normal_vs_Neural_Tube_Defect
- Control_vs_ZYP_High_Dose
- Healthy_vs_RAS4
- Healthy_vs_RAS4
- Control_0d_vs_Treatment_180d
- CIDP_patient_vs_healthy_control
- Control_vs_DMXAA16h
- G1_Sheep_ASA_SAT_vs_G2_Sheep_GOM_VAT
- Control_0h_vs_GABA_0h
- Control_vs_Lactic_Acid
- Control_vs_TGF-beta_Treatment
- Normal_vs_Abnormal
- SAR-S_vs_SAR-R
- After_Calving_vs_21_Days_Before_Due_Date
- Inbreeding_Growth_Chamber_0_day_vs_Inbreeding_Growth_Chamber_92_day