Diff Profiles › MTBLS3003_0002_00000001

Sham_vs_UIR

Sham vs UIR

p-value ≤ 0.05 29 significant 2025-09-26 00:00:00 Study: MTBLS3003
176 Total Features
29 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS3003_0002_00000001
Linked study
MTBLS3003 — Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 21)
Comparison
Sham vs UIR
Group A
Control group with no induced injury or treatment.. Provides a reference point for evaluating the effects of UIR and UIR+FG treatments.
Group B
Group with unilateral kidney ischemia-reperfusion (UIR) induced.. Allows assessment of the effects of UIR on kidney function and structure.
Total features tested
176
Significant features
29
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
SJVWVCVZWMJXOK-NOJHDUNKSA-N 12-oxo-LTB4 down 0.09373 0.000856
KAQKFAOMNZTLHT-OZUDYXHBSA-N (5Z,13E)-(15S)-6,9alpha-Epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate down 0.1194 0.000733
WLJVNTCWHIRURA-UHFFFAOYSA-N PIMELIC ACID down 0.01558 0.0442
RFSUNEUAIZKAJO-ARQDHWQXSA-N beta-D-arabino-Hexulose up 5.793 0.00372
YSMODUONRAFBET-UHFFFAOYSA-N hydroxylysine up 6.519 0.00668
DQAKJEWZWDQURW-UHFFFAOYSA-N — up 4.73 0.00293
CVSVTCORWBXHQV-UHFFFAOYSA-N {[amino(iminio)methyl](methyl)amino}acetate down 0.3656 0.000319
UDMBCSSLTHHNCD-KQYNXXCUSA-N Adenosine-5'-monophosphoric acid up 2.944 0.000617
QUCHWTCTBHQQDU-UHFFFAOYSA-N 2-ammonio-4-oxopentanoate up 3.01 0.0025
UGQMRVRMYYASKQ-KQYNXXCUSA-N hypoxanthine <small>D</small>-riboside up 3.194 0.0133