Metabolic disorder and intestinal microflora dysbiosis in chronic inflammatory demyelinating polyradiculoneuropathy

Study details

Source ID

https://identifiers.org/metabolights:MTBLS5828

Title

Metabolic disorder and intestinal microflora dysbiosis in chronic inflammatory demyelinating polyradiculoneuropathy

Summary

CIDP linked to metabolic and microbiome changes.

Observation

Serum metabolic profile and gut microbiome structure in CIDP.

Findings

Bile acids and arachidonic acid metabolism disturbed; gut dysbiosis linked to CIDP.

Disease terms

bacterial infection, Chronic inflammatory demyelinating polyradiculoneuropathy, Metabolic disorder, microbial infection, CIDP, chronic inflammatory demyelinating polyradiculoneuropathy, immune-mediated neuropathy

Gene terms

—

Chemical terms

arachidonic acid, Bile acids, bile acids

Organisms

Ruminococcus gnavus, Klebsiella pneumonia, Bacteroides ovatus, Bacteroides caccae, Megamonas funiformis

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS5828.

{
  "@type": "Dataset",
  "go_id": [
    "https://identifiers.org/GO:0006954",
    "https://identifiers.org/GO:0006955",
    "https://identifiers.org/GO:0019369",
    "https://identifiers.org/GO:0008206"
  ],
  "go_kw": [
    "inflammation",
    "immune response",
    "arachidonic acid metabolism",
    "bile acid metabolism"
  ],
  "integmet_study": "MTBLS5828",
  "mesh_chemical_id": [
    "https://identifiers.org/mesh:D016718",
    "https://identifiers.org/mesh:D001647"
  ],
  "mesh_chemical_pubtator_kw": [
    "arachidonic acid",
    "Bile acids",
    "bile acids"
  ],
  "mesh_disease_id": [
    "https://identifiers.org/mesh:D001424",
    "https://identifiers.org/mesh:D020277",
    "https://identifiers.org/mesh:D008659",
    "https://identifiers.org/mesh:D015163",
    "https://identifiers.org/mesh:C567355"
  ],
  "mesh_disease_pubtator_kw": [
    "bacterial infection",
    "Chronic inflammatory demyelinating polyradiculoneuropathy",
    "Metabolic disorder",
    "microbial infection",
    "CIDP",
    "chronic inflammatory demyelinating polyradiculoneuropathy",
    "immune-mediated neuropathy"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:33038",
    "https://identifiers.org/taxonomy:573",
    "https://identifiers.org/taxonomy:28116",
    "https://identifiers.org/taxonomy:47678",
    "https://identifiers.org/taxonomy:437897"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "Ruminococcus gnavus",
    "Klebsiella pneumonia",
    "Bacteroides ovatus",
    "Bacteroides caccae",
    "Megamonas funiformis"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS5828",
  "study_findings": "Bile acids and arachidonic acid metabolism disturbed; gut dysbiosis linked to CIDP.",
  "study_observation": "Serum metabolic profile and gut microbiome structure in CIDP.",
  "study_summary": "CIDP linked to metabolic and microbiome changes.",
  "study_title_original": "Metabolic disorder and intestinal microflora dysbiosis in chronic inflammatory demyelinating polyradiculoneuropathy"
}