Diff Profiles › MTBLS3628_0001_00000004

Normal_control_no_tumor_vs_FH_deficient_RCC

Normal_control_no_tumor vs FH_deficient_RCC

p-value ≤ 0.05 53 significant 2025-09-26 00:00:00 Study: MTBLS3628
251 Total Features
53 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS3628_0001_00000004
Linked study
MTBLS3628 — Distinct succinate modifying products are clinically diagnostic and prognostic biomarkers for fumarate hydratase deficient renal cell carcinoma
Comparison
Normal_control_no_tumor vs FH_deficient_RCC
Group A
Samples from healthy individuals with no tumor.. Provides a reference for identifying metabolic changes specific to RCC.
Group B
Samples from patients with FH-deficient renal cell carcinoma.. Key group for identifying metabolic biomarkers associated with FH-deficient RCC.
Total features tested
251
Significant features
53
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
NAQGHJTUZRHGAC-ZZZDFHIKSA-N 5'-Phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole up 626.7 0.00957
BGJFEKXALPJEGN-XVFCMESISA-N 2-[[N'-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]carbamimidoyl]-methylamino]acetic acid up 15.3 2.59e-05
SUHOQUVVVLNYQR-UHFFFAOYSA-N glycerophosphoric acid choline ester down 0.2237 1.25e-06
VKGZCEJTCKHMRL-VWJPMABRSA-N <em>N</em>-(9-β-<small>D</small>-ribofuranosyl-9<em>H</em>-purin-6-yl)-<small>L</small>-aspartic acid up 18.05 0.000923
WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-Glucose up 4.63 3.39e-05
SQVRNKJHWKZAKO-LUWBGTNYSA-N Aceneuramic acid up 3.555 6.19e-06
OEYIOHPDSNJKLS-UHFFFAOYSA-N Choline down 0.2608 1.73e-05
JKMHFZQWWAIEOD-UHFFFAOYSA-N 2-[4-(2-hydroxyethyl)piperazin-4-ium-1-yl]ethanesulfonate down 0.3462 1.61e-05
ODHCTXKNWHHXJC-VKHMYHEASA-N (−)-2-pyrrolidone-5-carboxylic acid down 0.3734 5.45e-05
RWQNBRDOKXIBIV-UHFFFAOYSA-N 5-Methyluracil up 1.968 3.6e-06