Metabolite details
Reactome pathways
- R-HSA-110329 - Cleavage of the damaged pyrimidine
- R-HSA-1430728 - Metabolism
- R-HSA-15869 - Metabolism of nucleotides
- R-HSA-382551 - Transport of small molecules
- R-HSA-425397 - Transport of vitamins, nucleosides, and related molecules
- R-HSA-425407 - SLC-mediated transmembrane transport
- R-HSA-73614 - Pyrimidine salvage
- R-HSA-73621 - Pyrimidine catabolism
- R-HSA-73884 - Base Excision Repair
- R-HSA-73894 - DNA Repair
- R-HSA-73928 - Depyrimidination
- R-HSA-73929 - Base-Excision Repair, AP Site Formation
- R-HSA-83936 - Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
- R-HSA-8956319 - Nucleotide catabolism
- R-HSA-8956321 - Nucleotide salvage
Observed in studies
- Biological effect of chronic mistranslation in mammalian cells
- Absence of tmRNA Increases the Persistence to Cefotaxime and the Intercellular Accumulation of Metabolite GlcNAc in <i>Aeromonas veronii</i>.
- Absence of tmRNA increases the persistence to cefotaxime by upregulating the metabolites GlcNAc in Aeromonas veronii
- Hfq Regulates Efflux Pump Expression and Purine Metabolic Pathway to Increase the Trimethoprim Resistance in Aeromonas veronii
- Jejunal inflammatory cytokines, barrier proteins and microbiome-metabolome responses to early supplementary feeding of Bamei suckling piglets
- The impact of slyA on cell metabolism of Salmonella Typhimurium: a joint study of transcriptomics and
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Escherichia coli assays)
- Metabolomic profiling reveals the effects of early-life lactoferrin intervention on protein synthesis, energy production and antioxidative capacity in the liver of suckling piglets
- Model-driven multi-omic data analysis elucidates metabolic immunomodulators of macrophage activation
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Klebsiella pneumoniae assays)
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Streptococcus pneumoniae assays)
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Streptococcus pyogenes assays)
- Multi-Omics Analysis Reveals Disturbance of Nanosecond Pulsed Electric Field in the Serum Metabolic Spectrum and Gut Microbiota
- Transcriptional differentiation of Trypanosoma brucei during in vitro acquisition of resistance to acoziborole
- Metabolic Dynamics in <i>Escherichia coli</i>-Based Cell-Free Systems
- Integrated Analyses of the Gut Microbiota, Intestinal Permeability and Serum Metabolome Phenotype in Rats with Alcohol Withdrawal Syndrome
- Microbial Diversity and Non-volatile Metabolites Profile of Low-Temperature Sausage Stored at Room Temperature
- Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 21)
- Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 10)
- Jasmonate-mediated stomatal closure under elevated CO2 revealed by time-resolved metabolomics
- Metabolomics Analysis of the Effect of GAT-2 Deficiency on Th1 Cells in Mice
- Analysis of Growth Phases of Enterotoxigenic Escherichia coli Reveals a Distinct Transition Phase before Entry into Early Stationary Phase with Shifts in Tryptophan, Fucose, and Putrescine Metabolism and Degradation of Neurotransmitter Precursors
- Metabolomics and lipidomics reveal perturbation of sphingolipid metabolism by a novel anti-trypanosomal 3-(oxazolo[4,5-b]pyridine-2-yl)anilide
- Distinct succinate modifying products are clinically diagnostic and prognostic biomarkers for fumarate hydratase deficient renal cell carcinoma
- Gut microbiome drives individual memory variation in bumblebees
- Mechanical force promotes dimethylarginine dimethylaminohydrolase 1-mediated hydrolysis of the metabolite asymmetric dimethylarginine to enhance bone formation
- Diallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice
- Long-term low-dose ionizing radiation induced chromosome-aberration-specific metabolic phenotype changes in radiation workers
- Metabolism Disorder Promotes Isoproterenol-induced Myocardial Injury in Mice with High Temperature and High Humidity and High-Fat Diet
- Exercise-generated β-aminoisobutyric acid (BAIBA) reduces cardiomyocytes metabolic stress and apoptosis caused by mitochondrial dysfunction through the miR-208b/AMPK pathway
- Metabolic profilings of rat INS-1 β-cells under changing levels of essential amino acids
- Effects of Radiofrequency Field from 5G Communications on fecal microbiome and metabolome profiles in mice
- Comparative Analysis of Host Metabolic Alterations in Murine Malaria Models with Uncomplicated or Severe Malaria
- Auricularia auricula polysaccharides reduce obesity in mice through gut commensal Papillibacter cinnamivorans
- Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors
- Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Feces metabolomics)
- Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Brain tissue metabolomics)
- Sodium Butyrate mediates Histone Crotonylation and Alleviated Neonatal Rats Hypoxic-Ischemic Brain Injury Through Gut-Brain Axis (untargeted fecal metabolomics)
- Mechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis
- Inorganic Carbon Limitation in Cells of the Wild Type and Photorespiratory Mutants of the Cyanobacterium Synechocystis sp. Strain PCC 6803
- Multiomic analysis revealed the potential role of rumen microbes in heat stress
- Effect of heat stress on serum enzyme activity, antioxidant capacity and immune parameter metabolomics datasets in Holstein cows at different growth stages
- Transcriptomic dynamics control rapid transition of core crop functions in 'lactating' pigeon
- Effects of Centella asiatica extract on antioxidant status and liver metabolome of rotenone-treated rats using GC-MS
- PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis.
- Alterations in the gut microbiota and metabolomics of seafarers after a six-month sea voyage
- Bile acid is a significant host factor shaping the gut microbiome of diet induced obese mice (untargeted metabolome profile assay)
- Integrated Proteomic and Metabolomic Analyses Show Differential Effects of Glucose Availability in Marine <i>Synechococcus</i> and <i>Prochlorococcus</i>.
- Metabolic disorder and intestinal microflora dysbiosis in chronic inflammatory demyelinating polyradiculoneuropathy
- DNA-PKcs drives CKD progression by activating TAF7/RAPTOR/mTORC1 signaling-mediated metabolic reprogramming
- A Pilot Characterization of the Human Chronobiome
- Comparative metabolomic analysis of exudates of microcystin-producing and microcystin-free Microcystis aeruginosa strains
- Extracellular-acidosis restricts one-carbon metabolism and preserves T cell stemness
- PatA mediates biofilm formation and drugs resistance through regulating the synthesis of glycolipids and lipids in mycobacterium PatA mediates a novel mycolic acid synthesis pathway and regulates biofilm formation in mycobacterium
- Metabolic changes associated with tick-microbe interactions
- TGF-β uncouples glycolysis and inflammation in macrophages and controls the survival during sepsis
- Unraveling the metabolic effects of benzophenone-3 on the endosymbiotic dinoflagellate Cladocopium goreaui
- Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice
- Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction
- Disturbed Microbiota-Metabolites-Immune Interaction Network is Associated with Olfactory Dysfunction in Patients with Chronic Rhinosinusitis
- L-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS negative mode)
- Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency.
- Plasma metabolite changes in dairy cows during parturition identified using untargeted metabolomics.
Observed in differential profiles
- rps2_wildtype_vs_rps2_A226Y
- Wild_Type_vs_tmRNA_Deletion
- Wild_Type_vs_tmRNA_Knockout
- Wild_Type_vs_tmRNA_Knockout
- Wild_type_vs_hfq
- Wild_type_vs_hfq
- Supplementary_feeding_vs_Control
- slyA_vs_wild_type
- RPMI_B36_vs_Pooled_Sera_B36
- RPMI_B36_vs_Pooled_Sera_B36
- Control_Day_8_vs_Lactoferrin_Day_8
- G1_Klebsiella_pneumoniae_AJ218_RPMI_vs_G2_Klebsiella_pneumoniae_AJ218_Pooled_sera
- G1_Klebsiella_pneumoniae_AJ218_RPMI_vs_G2_Klebsiella_pneumoniae_AJ218_Pooled_sera
- G1_Pooled_Sera_Blood_4559_vs_G2_RPMI_Glucose_Blood_4559
- G1_Pooled_Sera_Blood_4559_vs_G2_RPMI_Glucose_Blood_4559
- G1_RPMI_modified_Blood_M1T1_5448_vs_G2_Pooled_sera_Blood_M1T1_5448
- G1_RPMI_modified_Blood_M1T1_5448_vs_G2_Pooled_sera_Blood_M1T1_5448
- Control_vs_Lipopolysaccharide_stimulated
- Control_vs_nsPEF_7_day
- WT_vs_WT_Aco
- G1_Exp1_0_hours_vs_G2_Exp1_6_hours
- Alcohol_Treatment_vs_Control
- Control_vs_Day_12
- Sham_vs_UIR
- Sham_vs_UIR
- 400ppm_0min_vs_800ppm_60min
- GAT-2_Knockout_vs_Wild_Type
- E1777_Intracellular_MidLog_vs_E1777_Intracellular_EarlyStationary
- Control_vs_OXPA_Treatment
- Control_vs_OXPA_Treatment
- Normal_control_no_tumor_vs_FH_deficient_RCC
- Hindgut_Control_vs_Lactobacillus_apis
- Control_vs_Exercise
- G1_PBS_vs_G2_DSS
- LLIR_vs_Control
- Control_vs_Isoproterenol
- Sham_vs_Heart_Failure_Sedentary
- G1_Control_vs_G2_Arginine_Addition
- Sham_vs_Radiofrequency
- Uninfected_BALB/c_vs_Plasmodium_yoelii_17XL_BALB/c
- Basal_vs_High_Fat
- Wild_Type_vs_Gene_Knockout
- Normal_vs_Neural_Tube_Defect
- Normal_vs_Neural_Tube_Defect
- Normal_vs_Neural_Tube_Defect
- Sham_vs_HIBD
- Control_vs_ZYP_High_Dose
- Dc-N_vs_Dc-HS
- Dcs_N_vs_Dcs_HS
- Male_19_days_vs_Male_1_day
- Control_vs_Treatment
- Control_0d_vs_Treatment_180d
- MCF-7_WT_vs_MCF-7_PKM2_KO
- Normal_Diet_vs_High-fat_Diet
- Normal_Diet_vs_High-fat_Diet
- Normal_Diet_vs_High-fat_Diet
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- CIDP_patient_vs_healthy_control
- DNA-PK_KO_UUO_vs_DNA-PK_KO_Control
- WT_vs_sll0404.ko
- Plasma_0h_vs_Plasma_48h
- MC-producing_Exponential_vs_MC-free_Exponential
- Control_vs_Lactic_Acid
- wild_type_vs_patA_deletion
- Uninfected_1h_vs_Anaplasma_phagocytophilum_1h
- Control_vs_TGF-beta_Treatment
- Control_vs_BP3_Low_Concentration
- ASD_Fecal_vs_TD_Fecal
- Arginine_Replenished_Ctrl_vs_Arginine_Starved_48h
- Normal_vs_Abnormal
- SAR-R_vs_SAR-S
- WT_vs_ErbB2_KI
- After_Calving_vs_21_Days_Before_Due_Date