Effects of Centella asiatica extract on antioxidant status and liver metabolome of rotenone-treated rats using GC-MS

Study details

Source ID

https://identifiers.org/metabolights:MTBLS522

Title

Effects of Centella asiatica extract on antioxidant status and liver metabolome of rotenone-treated rats using GC-MS

Summary

Centella asiatica effects on rotenone-treated rat liver.

Observation

Effects of ECa233 on liver metabolome and antioxidant status.

Findings

ECa233 inhibited lipid peroxidation, increased catalase, and protected against rotenone toxicity.

Disease terms

toxicity

Gene terms

catalase

Chemical terms

Pipecolinic acid, madecassoside, lipid, asiaticoside, triterpenoids, Centella asiatica extract, pipecolinic acid, rotenone

Organisms

rat, Centella asiatica, Rats, rats

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS522.

{
  "@type": "Dataset",
  "integmet_study": "MTBLS522",
  "mesh_chemical_id": [
    "https://identifiers.org/mesh:C031345",
    "https://identifiers.org/mesh:C093443",
    "https://identifiers.org/mesh:D008055",
    "https://identifiers.org/mesh:C004446",
    "https://identifiers.org/mesh:D014315",
    "https://identifiers.org/mesh:C526146",
    "https://identifiers.org/mesh:D012402"
  ],
  "mesh_chemical_pubtator_kw": [
    "Pipecolinic acid",
    "madecassoside",
    "lipid",
    "asiaticoside",
    "triterpenoids",
    "Centella asiatica extract",
    "pipecolinic acid",
    "rotenone"
  ],
  "mesh_disease_id": [
    "https://identifiers.org/mesh:D064420"
  ],
  "mesh_disease_pubtator_kw": [
    "toxicity"
  ],
  "mesh_gene_id": [
    "https://identifiers.org/ncbigene:24248"
  ],
  "mesh_gene_pubtator_kw": [
    "catalase"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:10116",
    "https://identifiers.org/taxonomy:48106"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "rat",
    "Centella asiatica",
    "Rats",
    "rats"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS522",
  "study_findings": "ECa233 inhibited lipid peroxidation, increased catalase, and protected against rotenone toxicity.",
  "study_observation": "Effects of ECa233 on liver metabolome and antioxidant status.",
  "study_summary": "Centella asiatica effects on rotenone-treated rat liver.",
  "study_title_original": "Effects of Centella asiatica extract on antioxidant status and liver metabolome of rotenone-treated rats using GC-MS"
}