Diff Profiles › MTBLS4980_0002_00000006

Control_vs_ZYP_High_Dose

Control vs ZYP_High_Dose

p-value ≤ 0.05 774 significant 2025-09-26 00:00:00 Study: MTBLS4980
2813 Total Features
774 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS4980_0002_00000006
Linked study
MTBLS4980 — Mechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis
Comparison
Control vs ZYP_High_Dose
Group A
Control group with no disease and no ZYP treatment. Provides baseline data for comparison with disease and treatment groups.
Group B
Colitis model group treated with high dose ZYP. Evaluates the effect of high dose ZYP treatment on colitis.
Total features tested
2813
Significant features
774
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
NGLORVNWTNPBMU-UHFFFAOYSA-N 9-methoxy-6-phenyl-[1,3]dioxolo[4,5-g]chromen-8-one down 5.117e-09 0.000136
QRLBQXQEGMBXFM-JHIHKWCFSA-N Ustiloxin up 7.6e+08 0.00472
SPRXFHBMQQEVDG-ZHACJKMWSA-N 1-hydroxy-8-[(E)-3-hydroxy-3-methylbut-1-enyl]-3,6,7-trimethoxy-2-(3-methylbut-2-enyl)xanthen-9-one down 6.104e-06 0.000116
CAWXEEYDBZRFPE-UHFFFAOYSA-N Hexazinone down 7.913e-09 0.00366
RDVUSEMLHAXQRK-SMNQMHOSSA-N (2S,3S,4S,5R)-4-[[3-amino-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]-3,5,6-trihydroxyoxane-2-carboxylic acid up 1.851e+09 0.0147
AWLYBJONQDYQAK-QTJNYWJXSA-N — down 3.324e-09 0.0143
SAHCQBPGXQFTRA-MUTGBQBKSA-N GPI(18:2) up 5.339e+09 0.0416
IQOXOOYMXWDCEG-LXKJUNEMSA-N 4-methoxy-5-methyl-6-[(1Z,3E,5Z)-6-(4,7,8-trihydroxy-1,3,5-trimethyl-2,6-dioxabicyclo[3.2.1]octan-3-yl)hexa-1,3,5-trienyl]pyran-2-one down 0.03061 6.49e-07
VNLREARKISTOAD-ALCCZGGFSA-N butyl 3-[(Z)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-1,4,5-trihydroxycyclohexane-1-carboxylate up 107.9 2.9e-05
UKFQQYJAYUAYES-DTMHFWPESA-O tamoxifen <em>N</em>-glucuronide down 0.02203 2.76e-06