Diff Profiles › MTBLS4980_0001_00000006

Control_vs_ZYP_High_Dose

Control vs ZYP_High_Dose

p-value ≤ 0.05 578 significant 2025-09-26 00:00:00 Study: MTBLS4980
2292 Total Features
578 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS4980_0001_00000006
Linked study
MTBLS4980 — Mechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis
Comparison
Control vs ZYP_High_Dose
Group A
Control group with no disease and no ZYP treatment. Provides baseline data for comparison with disease and treatment groups.
Group B
Colitis model group treated with high dose ZYP. Evaluates the effect of high dose ZYP treatment on colitis.
Total features tested
2292
Significant features
578
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
DANFNCOJRRFMIO-UHFFFAOYSA-N 2-butan-2-yloxy-6-[[3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxymethyl]oxane-3,4,5-triol up 3.411e+08 0.000182
PHKYZFGDNGACRM-UHFFFAOYSA-N 15-hydroxy-13,14-dimethoxy-10-azatetracyclo[7.6.1.02,7.012,16]hexadeca-1(16),2,4,6,8,12,14-heptaen-11-one down 4.04e-09 0.00709
SHGAZHPCJJPHSC-YCNIQYBTSA-N (2<i>E</i>,4<i>E</i>,6<i>E</i>,8<i>E</i>)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenoic acid down 2.681e-08 0.021
JBVVDXJXIDYDMF-GVTADUIWSA-N (1S,2S,4R,8S,9S,11S,12S,13R,19R)-11,19-dihydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one down 0.03402 1.69e-07
QXRLQTRFEMAPRP-MDZDMXLPSA-N — down 0.02936 9.73e-07
VVQRJFUYBNCTQX-UHFFFAOYSA-N [16-[1-(4,5-dimethyl-6-oxo-2,3-dihydropyran-2-yl)ethyl]-6,12-dihydroxy-2,17-dimethyl-3-oxo-8,15-dioxahexacyclo[9.8.0.02,7.07,9.012,17.014,16]nonadec-4-en-13-yl] acetate down 0.01065 2.29e-05
KRHHFPJGGBLAAH-MYBCZMNMSA-N (2R)-2-[(1S)-1-[(1S,3R,8S,9S,10R,13S,14S,17R)-1-hydroxy-10,13-dimethyl-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethyl]-5-(hydroxymethyl)-4-methyl-2,3-dihydropyran-6-one down 0.01566 7.96e-05
BSILZSYJTIBPFN-CNFGNZGNSA-N 3,8-dihydroxy-16,17-dimethoxy-15-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxytricyclo[12.3.1.12,6]nonadeca-1(17),2,4,6(19),14(18),15-hexaen-9-one down 0.03644 9.08e-06
LVCMXFSJTNPFHH-FRCNGJHJSA-N 6-[3-[(1E,3E,5E,7E)-8-carboxy-3,7-dimethylocta-1,3,5,7-tetraenyl]-2,4,4-trimethylcyclohex-2-en-1-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid down 0.005597 0.000651
NFDVJYPMLVMXRR-UHFFFAOYSA-N 1,2-dimethoxy-4,5,6,6a-tetradehydro-9,10-(methylenedioxy)noraprophin-7-one down 0.003217 0.00137