Mechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis

Study details

Source ID

https://identifiers.org/metabolights:MTBLS4980

Title

Mechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis

Summary

Zhuyu Pill effects on colitis and cholestasis.

Observation

Colitis rat model, fecal metabolism, and microbiota changes.

Findings

Tryptophan metabolism and microbiota changes are core targets of ZYP.

Disease terms

inflammatory, diseases of the, cholestasis, colitis

Gene terms

—

Chemical terms

tryptophan

Organisms

rat, Tetradium ruticarpum, Coptis chinensis Franch

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS4980.

{
  "@type": "Dataset",
  "go_id": [
    "https://identifiers.org/GO:0006568",
    "https://identifiers.org/GO:0008152"
  ],
  "go_kw": [
    "tryptophan metabolism",
    "metabolism"
  ],
  "integmet_study": "MTBLS4980",
  "mesh_chemical_id": [
    "https://identifiers.org/mesh:D014364"
  ],
  "mesh_chemical_pubtator_kw": [
    "tryptophan"
  ],
  "mesh_disease_id": [
    "https://identifiers.org/mesh:D007249",
    "https://identifiers.org/mesh:D004194",
    "https://identifiers.org/mesh:D002779",
    "https://identifiers.org/mesh:D003092"
  ],
  "mesh_disease_pubtator_kw": [
    "inflammatory",
    "diseases of the",
    "cholestasis",
    "colitis"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:10116",
    "https://identifiers.org/taxonomy:354523",
    "https://identifiers.org/taxonomy:261450"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "rat",
    "Tetradium ruticarpum",
    "Coptis chinensis Franch"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS4980",
  "study_findings": "Tryptophan metabolism and microbiota changes are core targets of ZYP.",
  "study_observation": "Colitis rat model, fecal metabolism, and microbiota changes.",
  "study_summary": "Zhuyu Pill effects on colitis and cholestasis.",
  "study_title_original": "Mechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis"
}