Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice

Study details

Source ID

https://identifiers.org/metabolights:MTBLS726

Title

Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice

Summary

ASD microbiota affects mouse behavior and brain.

Observation

Gut microbiota from ASD and TD individuals transplanted into mice.

Findings

ASD microbiota induces autistic behaviors and gene splicing; metabolites modulate behaviors.

Disease terms

Autism spectrum disorder, behavioral abnormalities, autistic behaviors, Autism Spectrum Disorder, ASD

Gene terms

—

Chemical terms

—

Organisms

Human, mice, human, mouse, Mice

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS726.

{
  "@type": "Dataset",
  "integmet_study": "MTBLS726",
  "mesh_disease_id": [
    "https://identifiers.org/mesh:D000067877",
    "https://identifiers.org/mesh:D001523",
    "https://identifiers.org/mesh:D001321"
  ],
  "mesh_disease_pubtator_kw": [
    "Autism spectrum disorder",
    "behavioral abnormalities",
    "autistic behaviors",
    "Autism Spectrum Disorder",
    "ASD"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:9606",
    "https://identifiers.org/taxonomy:10090"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "Human",
    "mice",
    "human",
    "mouse",
    "Mice"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS726",
  "study_findings": "ASD microbiota induces autistic behaviors and gene splicing; metabolites modulate behaviors.",
  "study_observation": "Gut microbiota from ASD and TD individuals transplanted into mice.",
  "study_summary": "ASD microbiota affects mouse behavior and brain.",
  "study_title_original": "Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice"
}