Transcriptional differentiation of Trypanosoma brucei during in vitro acquisition of resistance to acoziborole

Study details

Source ID

https://identifiers.org/metabolights:MTBLS2559

Title

Transcriptional differentiation of Trypanosoma brucei during in vitro acquisition of resistance to acoziborole

Summary

Acoziborole resistance in Trypanosoma brucei studied.

Observation

Transcriptional differentiation in acoziborole-resistant Trypanosoma brucei.

Findings

AcoR cells show procyclic-like transcriptome; no CPSF3 transcript changes.

Disease terms

HAT, neglected tropical disease, Human African Trypanosomiasis

Gene terms

—

Chemical terms

sinefungin

Organisms

Trypanosoma brucei

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS2559.

{
  "@type": "Dataset",
  "go_id": [
    "https://identifiers.org/GO:0008152"
  ],
  "go_kw": [
    "metabolism"
  ],
  "integmet_study": "MTBLS2559",
  "mesh_chemical_id": [
    "https://identifiers.org/mesh:C006235"
  ],
  "mesh_chemical_pubtator_kw": [
    "sinefungin"
  ],
  "mesh_disease_id": [
    "https://identifiers.org/mesh:D014353",
    "https://identifiers.org/mesh:D058069"
  ],
  "mesh_disease_pubtator_kw": [
    "HAT",
    "neglected tropical disease",
    "Human African Trypanosomiasis"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:5691"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "Trypanosoma brucei"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS2559",
  "study_findings": "AcoR cells show procyclic-like transcriptome; no CPSF3 transcript changes.",
  "study_observation": "Transcriptional differentiation in acoziborole-resistant Trypanosoma brucei.",
  "study_summary": "Acoziborole resistance in Trypanosoma brucei studied.",
  "study_title_original": "Transcriptional differentiation of Trypanosoma brucei during in vitro acquisition of resistance to acoziborole"
}