Diff Profiles › MTBLS2559_0001_00000001

WT_vs_WT_Aco

WT vs WT_Aco

p-value ≤ 0.05 134 significant 2025-09-26 00:00:00 Study: MTBLS2559
739 Total Features
134 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS2559_0001_00000001
Linked study
MTBLS2559 — Transcriptional differentiation of Trypanosoma brucei during in vitro acquisition of resistance to acoziborole
Comparison
WT vs WT_Aco
Group A
Wild-type Trypanosoma brucei samples without treatment.. Serves as the reference point for all treatment comparisons.
Group B
Wild-type Trypanosoma brucei samples treated with Acoziborole.. Demonstrates the effect of Acoziborole on wild-type organisms.
Total features tested
739
Significant features
134
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
PTYGDEXEGLDNAZ-UHFFFAOYSA-N 4-luoro-N-(1-hydroxy-3,3-dimethyl-2,1-benzoxaborol-6-yl)-2-(triluoromethyl)benzamide down 1e-06 5.7e-06
AWNLUIGMHSSXHB-UHFFFAOYSA-N 2-(hydroxymethyl)-2H-uran-5-one down 0.1668 1.91e-05
IIQIOFVDFOLCHP-UHFFFAOYSA-N 2-[[2-[[1-(2,4-diamino-4-oxobutanoyl)pyrrolidine-2-carbonyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxypropanoic acid up 12.33 0.000827
JRLGPAXAGHMNOL-LURJTMIESA-N (2<i>S</i>)-2-acetamido-5-ammoniopentanoate down 0.186 0.00017
PXEKBQAJOBYINU-BYPYZUCNSA-N <em>N</em>-hydroxyvaline down 0.1192 0.00235
GIAZPLMMQOERPN-YUMQZZPRSA-N valylproline up 7.816 0.00316
KIQYUSYSJTUGFZ-LSLODQAYSA-N Phosphatidylinositol(36:4) up 2.916 4.85e-05
GUAHPAJOXVYFON-UHFFFAOYSA-N 8-ammonio-7-oxononanoate down 0.2437 0.00055
SSYBNWFXCFNRFN-GUBZILKMSA-N <small>L</small>-Val-<small>L</small>-Pro-<small>L</small>-Ser up 4.971 0.00146
KUTPGXNAAOQSPD-LPEHRKFASA-N (2R)-1-[(2S)-2-[[(2S)-2-amino-4-carboxybutanoyl]amino]-4-carboxybutanoyl]pyrrolidine-2-carboxylic acid down 0.09565 0.0141