wild_type_vs_patA_deletion

wild_type vs patA_deletion

p-value ≤ 0.05 53 significant 2025-09-26 00:00:00 Study: MTBLS6758
206 Total Features
53 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS6758_0002_00000002
Linked study
MTBLS6758 — PatA mediates biofilm formation and drugs resistance through regulating the synthesis of glycolipids and lipids in mycobacterium PatA mediates a novel mycolic acid synthesis pathway and regulates biofilm formation in mycobacterium
Comparison
wild_type vs patA_deletion
Group A
Wild type samples.. Provides a baseline for comparing the effects of patA deletion and overexpression.
Group B
Samples with patA deletion genotype.. Helps in understanding the role of patA in drug resistance and biofilm formation.
Total features tested
206
Significant features
53
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
OAPVIBHQRYFYSE-UHFFFAOYSA-N 5-phenylpyridin-2-amine down 0.3046 8e-08
QEOYMVJQPHELJB-YXHLBBQNSA-N Diacylglycerol(20:0/20:5n3) up 3.799 3.27e-06
NKSOSPOXQKNIKJ-CLFAGFIQSA-N 2-[(Z)-octadec-9-enoyl]oxyethyl (Z)-octadec-9-enoate up 4.436 1.74e-05
HSNPMXROZIQAQD-GBURMNQMSA-N TLC-S down 0.1348 0.00053
RUDATBOHQWOJDD-BYRKYSOESA-N (4R)-4-[(3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid up 2.445 5.8e-08
BQVUABVGYYSDCJ-UHFFFAOYSA-N 2-[(2-amino-4-methylpentanoyl)amino]-3-(1H-indol-3-yl)propanoic acid down 0.3679 1.37e-06
BVIAOQMSVZHOJM-UHFFFAOYSA-N N,N-Dimethyl-6-aminopurine down 0.4349 4.71e-06
IERHLVCPSMICTF-XVFCMESISA-N Cytidine-5'-monophosphate down 0.3275 0.000236
YAICYXFUKKMAKO-DBQWNMKUSA-N (6aS,10aS)-7-prop-2-enyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-g]quinoline-9-carboxylic acid down 0.4995 4e-06
DLJKPYFALUEJCK-IIELGFQLSA-N (15<i>S</i>)-15-methyl-PGF<small><sub>2α</sub></small> up 2.341 0.000115