wild_type_vs_patA_deletion

wild_type vs patA_deletion

p-value ≤ 0.05 34 significant 2025-09-26 00:00:00 Study: MTBLS6758
256 Total Features
34 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS6758_0001_00000002
Linked study
MTBLS6758 — PatA mediates biofilm formation and drugs resistance through regulating the synthesis of glycolipids and lipids in mycobacterium PatA mediates a novel mycolic acid synthesis pathway and regulates biofilm formation in mycobacterium
Comparison
wild_type vs patA_deletion
Group A
Wild type samples.. Provides a baseline for comparing the effects of patA deletion and overexpression.
Group B
Samples with patA deletion genotype.. Helps in understanding the role of patA in drug resistance and biofilm formation.
Total features tested
256
Significant features
34
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
FRGRNGNKLISCCU-UHFFFAOYSA-N 2-(1-ethoxyethoxy)propanoic acid up 6.207 4.18e-07
KJTLQQUUPVSXIM-UHFFFAOYSA-N β,δ-dihydroxy-β-methylvaleric acid up 4.292 2.08e-06
UQCNKQCJZOAFTQ-ISWURRPUSA-N Oxymorphone down 0.1041 0.00232
ZTNFQEXYTMNFHG-SOFXVBFTSA-N Phosphatidylserine(36:4) up 4.105 7.54e-05
RFVNOJDQRGSOEL-UHFFFAOYSA-N ethylene glycol stearate down 0.2603 0.00126
DEFJQIDDEAULHB-QWWZWVQMSA-N (2R)-2-{[(2R)-2-ammoniopropanoyl]amino}propanoate down 0.4729 9.63e-05
DGYMUJFBJOIXMY-UHFFFAOYSA-N down 0.3227 0.00405
LQCLVBQBTUVCEQ-QTFUVMRISA-N Triacetyloleandomycin down 0.2831 0.00819
BIEOSECQPGGZMF-NAIWXXGBSA-N Lysophosphatidylcholine(22:5n3/0:0) down 0.3611 0.00687
IVYPNXXAYMYVSP-UHFFFAOYSA-N 3-hydroxymethylindole down 0.4066 0.00469