Diff Profiles › MTBLS3056_0002_00000001

Sham_vs_UIR

Sham vs UIR

p-value ≤ 0.05 74 significant 2025-09-26 00:00:00 Study: MTBLS3056
135 Total Features
74 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS3056_0002_00000001
Linked study
MTBLS3056 — Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 10)
Comparison
Sham vs UIR
Group A
Control group with no induced injury or treatment.. Provides a reference point for evaluating the effects of UIR and UIR+FG treatments.
Group B
Group with unilateral kidney ischemia-reperfusion (UIR) induced.. Allows for the assessment of the effects of UIR on kidney function and structure.
Total features tested
135
Significant features
74
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
JYGXADMDTFJGBT-VWUMJDOOSA-N Kendall's compound F up 355.7 1.49e-07
RZZPDXZPRHQOCG-OJAKKHQRSA-N Citicoline up 59.25 2.03e-06
RITKHVBHSGLULN-WHFBIAKZSA-N Glu(-Cys) up 149.6 5.11e-05
ZJUKTBDSGOFHSH-WFMPWKQPSA-N 5'-S-[(3S)-3-azaniumyl-3-carboxylatopropyl]-5'-thioadenosine up 28.31 2.26e-06
YSMODUONRAFBET-UHFFFAOYSA-N hydroxylysine up 16.24 4.88e-06
FUZOZPRKGAXGOB-WDSKDSINSA-N (2S)-2-amino-5-[[(1S)-1-carboxypropyl]amino]-5-oxopentanoic acid up 18.81 1.13e-05
FHQDWPCFSJMNCT-UHFFFAOYSA-N Ntau-Methylhistamine up 18.45 1.91e-05
ZMJGSOSNSPKHNH-UHFFFAOYSA-N pyridoxamine 5'-(dihydrogen phosphate) up 124.4 0.00144
QIAFMBKCNZACKA-UHFFFAOYSA-N Benzamidoessigsäure up 20.07 5.2e-05
UTYVDVLMYQPLQB-UHFFFAOYSA-N Phenaceturic acid up 7.974 1.72e-05