Metabolite details
Reactome pathways
- R-HSA-112311 - Neurotransmitter clearance
- R-HSA-112315 - Transmission across Chemical Synapses
- R-HSA-112316 - Neuronal System
- R-HSA-1266738 - Developmental Biology
- R-HSA-1280218 - Adaptive Immune System
- R-HSA-1428517 - Aerobic respiration and respiratory electron transport
- R-HSA-1430728 - Metabolism
- R-HSA-1474165 - Reproduction
- R-HSA-1483191 - Synthesis of PC
- R-HSA-1483206 - Glycerophospholipid biosynthesis
- R-HSA-1483257 - Phospholipid metabolism
- R-HSA-1500620 - Meiosis
- R-HSA-1500931 - Cell-Cell communication
- R-HSA-156580 - Phase II - Conjugation of compounds
- R-HSA-156581 - Methylation
- R-HSA-1614635 - Sulfur amino acid metabolism
- R-HSA-162582 - Signal Transduction
- R-HSA-163841 - Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation
- R-HSA-1640170 - Cell Cycle
- R-HSA-1643685 - Disease
- R-HSA-168256 - Immune System
- R-HSA-195721 - Signaling by WNT
- R-HSA-196741 - Cobalamin (Cbl, vitamin B12) transport and metabolism
- R-HSA-196807 - Nicotinate metabolism
- R-HSA-196849 - Metabolism of water-soluble vitamins and cofactors
- R-HSA-196854 - Metabolism of vitamins and cofactors
- R-HSA-201681 - TCF dependent signaling in response to WNT
- R-HSA-201722 - Formation of the beta-catenin:TCF transactivating complex
- R-HSA-203927 - MicroRNA (miRNA) biogenesis
- R-HSA-209776 - Metabolism of amine-derived hormones
- R-HSA-209905 - Catecholamine biosynthesis
- R-HSA-209931 - Serotonin and melatonin biosynthesis
- R-HSA-211000 - Gene Silencing by RNA
- R-HSA-211859 - Biological oxidations
- R-HSA-212165 - Epigenetic regulation of gene expression
- R-HSA-212300 - PRC2 methylates histones and DNA
- R-HSA-212436 - Generic Transcription Pathway
- R-HSA-2142789 - Ubiquinol biosynthesis
- R-HSA-2187338 - Visual phototransduction
- R-HSA-2262752 - Cellular responses to stress
- R-HSA-2299718 - Condensation of Prophase Chromosomes
- R-HSA-2408499 - Formation of selenosugars for excretion
- R-HSA-2408508 - Metabolism of ingested SeMet, Sec, MeSec into H2Se
- R-HSA-2408522 - Selenoamino acid metabolism
- R-HSA-2408552 - Methylation of MeSeH for excretion
- R-HSA-2514856 - The phototransduction cascade
- R-HSA-2514859 - Inactivation, recovery and regulation of the phototransduction cascade
- R-HSA-2559580 - Oxidative Stress Induced Senescence
- R-HSA-2559582 - Senescence-Associated Secretory Phenotype (SASP)
- R-HSA-2559583 - Cellular Senescence
- R-HSA-3214841 - PKMTs methylate histone lysines
- R-HSA-3214858 - RMTs methylate histone arginines
- R-HSA-3247509 - Chromatin modifying enzymes
- R-HSA-3700989 - Transcriptional Regulation by TP53
- R-HSA-379397 - Enzymatic degradation of dopamine by COMT
- R-HSA-379401 - Dopamine clearance from the synaptic cleft
- R-HSA-382551 - Transport of small molecules
- R-HSA-388841 - Regulation of T cell activation by CD28 family
- R-HSA-389661 - Glyoxylate metabolism and glycine degradation
- R-HSA-389948 - Co-inhibition by PD-1
- R-HSA-392499 - Metabolism of proteins
- R-HSA-418990 - Adherens junctions interactions
- R-HSA-421270 - Cell-cell junction organization
- R-HSA-425407 - SLC-mediated transmembrane transport
- R-HSA-427359 - SIRT1 negatively regulates rRNA expression
- R-HSA-427389 - ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
- R-HSA-427413 - NoRC negatively regulates rRNA expression
- R-HSA-446728 - Cell junction organization
- R-HSA-453274 - Mitotic G2-G2/M phases
- R-HSA-4839726 - Chromatin organization
- R-HSA-5250913 - Positive epigenetic regulation of rRNA expression
- R-HSA-5250941 - Negative epigenetic regulation of rRNA expression
- R-HSA-5334118 - DNA methylation
- R-HSA-5358493 - Synthesis of diphthamide-EEF2
- R-HSA-549127 - SLC-mediated transport of organic cations
- R-HSA-556833 - Metabolism of lipids
- R-HSA-5578997 - Defective AHCY causes HMAHCHD
- R-HSA-5579029 - Metabolic disorders of biological oxidation enzymes
- R-HSA-5601884 - PIWI-interacting RNA (piRNA) biogenesis
- R-HSA-5633007 - Regulation of TP53 Activity
- R-HSA-5663205 - Infectious disease
- R-HSA-5668914 - Diseases of metabolism
- R-HSA-5673001 - RAF/MAP kinase cascade
- R-HSA-5676934 - Protein repair
- R-HSA-5683057 - MAPK family signaling cascades
- R-HSA-5684996 - MAPK1/MAPK3 signaling
- R-HSA-5693532 - DNA Double-Strand Break Repair
- R-HSA-5693565 - Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
- R-HSA-5693606 - DNA Double Strand Break Response
- R-HSA-597592 - Post-translational protein modification
- R-HSA-6782315 - tRNA modification in the nucleus and cytosol
- R-HSA-6782861 - Synthesis of wybutosine at G37 of tRNA(Phe)
- R-HSA-6787450 - tRNA modification in the mitochondrion
- R-HSA-6790901 - rRNA modification in the nucleus and cytosol
- R-HSA-6793080 - rRNA modification in the mitochondrion
- R-HSA-6804760 - Regulation of TP53 Activity through Methylation
- R-HSA-68875 - Mitotic Prophase
- R-HSA-68886 - M Phase
- R-HSA-69273 - Cyclin A/B1/B2 associated events during G2/M transition
- R-HSA-69275 - G2/M Transition
- R-HSA-69278 - Cell Cycle, Mitotic
- R-HSA-70921 - Histidine catabolism
- R-HSA-71288 - Creatine metabolism
- R-HSA-71291 - Metabolism of amino acids and derivatives
- R-HSA-71403 - Citric acid cycle (TCA cycle)
- R-HSA-72086 - mRNA Capping
- R-HSA-72306 - tRNA processing
- R-HSA-72312 - rRNA processing
- R-HSA-72764 - Eukaryotic Translation Termination
- R-HSA-72766 - Translation
- R-HSA-73857 - RNA Polymerase II Transcription
- R-HSA-73894 - DNA Repair
- R-HSA-74160 - Gene expression (Transcription)
- R-HSA-8868766 - rRNA processing in the mitochondrion
- R-HSA-8868773 - rRNA processing in the nucleus and cytosol
- R-HSA-8876725 - Protein methylation
- R-HSA-8878171 - Transcriptional regulation by RUNX1
- R-HSA-8936459 - RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
- R-HSA-8939211 - ESR-mediated signaling
- R-HSA-8939236 - RUNX1 regulates transcription of genes involved in differentiation of HSCs
- R-HSA-8953854 - Metabolism of RNA
- R-HSA-8953897 - Cellular responses to stimuli
- R-HSA-8978934 - Metabolism of cofactors
- R-HSA-9006931 - Signaling by Nuclear Receptors
- R-HSA-9009391 - Extra-nuclear estrogen signaling
- R-HSA-912446 - Meiotic recombination
- R-HSA-9638737 - Action of antimicrobials and antimicrobial resistance
- R-HSA-9640148 - Infection with Enterobacteria
- R-HSA-9645723 - Diseases of programmed cell death
- R-HSA-9648002 - RAS processing
- R-HSA-9678108 - SARS-CoV-1 Infection
- R-HSA-9679506 - SARS-CoV Infections
- R-HSA-9679514 - SARS-CoV-1 Genome Replication and Transcription
- R-HSA-9682706 - Replication of the SARS-CoV-1 genome
- R-HSA-9682708 - Transcription of SARS-CoV-1 sgRNAs
- R-HSA-9694516 - SARS-CoV-2 Infection
- R-HSA-9694631 - Maturation of nucleoprotein
- R-HSA-9694635 - Translation of Structural Proteins
- R-HSA-9694682 - SARS-CoV-2 Genome Replication and Transcription
- R-HSA-9694686 - Replication of the SARS-CoV-2 genome
- R-HSA-9694786 - Transcription of SARS-CoV-2 sgRNAs
- R-HSA-9709957 - Sensory Perception
- R-HSA-9710421 - Defective pyroptosis
- R-HSA-9748784 - Drug ADME
- R-HSA-9748787 - Azathioprine ADME
- R-HSA-9759218 - Cobalamin (Cbl) metabolism
- R-HSA-9759476 - Regulation of Homotypic Cell-Cell Adhesion
- R-HSA-9764265 - Regulation of CDH1 Expression and Function
- R-HSA-9764274 - Regulation of Expression and Function of Type I Classical Cadherins
- R-HSA-9764560 - Regulation of CDH1 Gene Transcription
- R-HSA-9764725 - Negative Regulation of CDH1 Gene Transcription
- R-HSA-9772572 - Early SARS-CoV-2 Infection Events
- R-HSA-9772573 - Late SARS-CoV-2 Infection Events
- R-HSA-9816359 - Maternal to zygotic transition (MZT)
- R-HSA-9818564 - Epigenetic regulation of gene expression by MLL3 and MLL4 complexes
- R-HSA-9820952 - Respiratory Syncytial Virus Infection Pathway
- R-HSA-9820965 - Respiratory syncytial virus (RSV) genome replication, transcription and translation
- R-HSA-9821993 - Replacement of protamines by nucleosomes in the male pronucleus
- R-HSA-9824439 - Bacterial Infection Pathways
- R-HSA-9824446 - Viral Infection Pathways
- R-HSA-9828642 - Respiratory syncytial virus genome transcription
- R-HSA-9841922 - MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
- R-HSA-9842860 - Regulation of endogenous retroelements
- R-HSA-9843940 - Regulation of endogenous retroelements by KRAB-ZFP proteins
- R-HSA-9843970 - Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
- R-HSA-9845323 - Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
- R-HSA-9851695 - Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes
- R-HSA-9854311 - Maturation of TCA enzymes and regulation of TCA cycle
- R-HSA-9909648 - Regulation of PD-L1(CD274) expression
- R-HSA-9909649 - Regulation of PD-L1(CD274) transcription
- R-HSA-9913143 - Antimicrobial resistance
- R-HSA-9917777 - Epigenetic regulation by WDR5-containing histone modifying complexes
- R-HSA-9937008 - Mitochondrial mRNA modification
Observed in studies
- Biological effect of chronic mistranslation in mammalian cells
- Distribution of RESV and its metabolite peaks in mouse tissues after oral and skin administration
- Resveratrol metabolism in HepG2 (human hepatocytes), HaCaT (human keratinocytes), and C2C12 (mouse myoblasts)
- Bioaccumulation of therapeutic drugs by human gut bacteria: cross-feeding metabolite analysis (FIA-MS) (E.rectale;S.salivarius assays)
- How Does the Seed Pre-germinative Metabolism Fight against Imbibition Damage; Emerging Roles of Fatty Acid Cohort and Antioxidant Defence
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Escherichia coli assays)
- Metabolic Dynamics of In Vitro CD8+ T Cell Activation.
- Multi-Omics Analysis Reveals Disturbance of Nanosecond Pulsed Electric Field in the Serum Metabolic Spectrum and Gut Microbiota
- Host autophagy mediates organ wasting and nutrient mobilization for tumor growth.
- SARS-CoV-2-reprogrammed metabolism and autophagy reduction uncover host-targeting antivirals
- Microbial Diversity and Non-volatile Metabolites Profile of Low-Temperature Sausage Stored at Room Temperature
- Changes and correlations of intestinal flora and liver metabolite profiles in mice with gallstones
- Multiomics of tomato glandular trichomes reveals distinct features of central carbon metabolism supporting high productivity of specialized metabolites
- Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 21)
- Metabolomics dataset of PPAR-pan treated rat liver (acyl-carnitine and aqueous metabolite assays)
- Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 10)
- Specific biomarkers for stochastic division patterns and starvation-induced quiescence under limited glucose levels in fission yeast
- Gut microbiome drives individual memory variation in bumblebees
- The Manchurian Walnut Genome: Insights into Juglone and Lipid Biosynthesis.
- Diallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice
- Exercise-generated β-aminoisobutyric acid (BAIBA) reduces cardiomyocytes metabolic stress and apoptosis caused by mitochondrial dysfunction through the miR-208b/AMPK pathway
- Multi-omic Profiling of Multi-Biosamples Reveals the Role of Amino Acid and Nucleotide Metabolism in Endometrial Cancer
- Metabolic profilings of rat INS-1 β-cells under changing levels of essential amino acids
- Homeostasis of the biosynthetic E. coli metabolome
- Comparative Analysis of Host Metabolic Alterations in Murine Malaria Models with Uncomplicated or Severe Malaria
- Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors
- Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Feces metabolomics)
- Interaction between Cervical Microbiota and Host Gene Regulation in Caesarean Section Scar Diverticulum
- Mechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis
- Multiomic analysis revealed the potential role of rumen microbes in heat stress
- Effect of heat stress on serum enzyme activity, antioxidant capacity and immune parameter metabolomics datasets in Holstein cows at different growth stages
- Diverse metabolic reactions activated during 58-hr fasting are revealed by non-targeted metabolomic analysis of human blood.
- GABA regulates IL-1β production in macrophages
- Extracellular-acidosis restricts one-carbon metabolism and preserves T cell stemness
- Metabolomic Analysis of Fission Yeast at the Onset of Nitrogen Starvation
- Genetic mapping and molecular mechanism behind color variation in the Asian vine snake
- Metabolic consequences of cobalamin scarcity in diatoms as revealed through metabolomics (Thalassiosira pseudonana study)
- Metabolic consequences of cobalamin scarcity in diatoms as revealed through metabolomics (Navicula pelliculosa study)
- Unexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites (Blood fraction)
- Unexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites (Blood plasma and RBC fractions)
- Changing environments and genetic variation: inbreeding does not compromise short-term physiological responses
Observed in differential profiles
- rps2_wildtype_vs_rps2_A226Y
- Control_Oral_Blood_vs_RESV_Oral_Blood
- Control_Oral_Blood_vs_RESV_Oral_Blood
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- G4_Eubacterium_rectale_DMSO_30_vs_G3_Eubacterium_rectale_Duloxetine_47
- Dry_Seed_vs_8h_Imbibed_Seed
- RPMI_B36_vs_Pooled_Sera_B36
- G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
- G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
- Control_vs_nsPEF_7_day
- G1_Frt_Ctrl_Day_6_vs_G3_Rasv12_Scrib_Day_6
- Calu3_Mock_DMEM_vs_Calu3_10uM_NIC
- Control_vs_Day_12
- Control_vs_Lithogenic_Diet
- Solanum_habrochaites_leaf_vs_glandular_trichome
- Sham_vs_UIR
- Control_vs_High
- Sham_vs_UIR
- G10_0_volume_percentage_vs_G1_2_volume_percentage
- Hindgut_Control_vs_Lactobacillus_apis
- Embryo_S1_vs_Embryo_S4
- G1_PBS_vs_G2_DSS
- Sham_vs_Heart_Failure_Sedentary
- Sham_vs_Heart_Failure_Sedentary
- Control_vs_Endometrial_Cancer
- G1_Control_vs_G2_Arginine_Addition
- Glu_BW25113_vs_Pyr_BW25113
- Uninfected_BALB/c_vs_Plasmodium_yoelii_17XL_BALB/c
- Wild_Type_vs_Gene_Knockout
- Normal_vs_Neural_Tube_Defect
- Control_vs_CSD
- Control_vs_ZYP_High_Dose
- Dc-N_vs_Dc-HS
- Dcs_N_vs_Dcs_HS
- Blood_10h_vs_Blood_58h
- Control_0h_vs_GABA_0h
- Control_vs_Lactic_Acid
- 0_min_vs_60_min
- Yellow_Skin_vs_Green_Skin
- Saturating_Limiting_vs_Saturating_Replete
- Saturating_Limiting_vs_Saturating_Replete
- Navicula_pelliculosa_Saturating_Limiting_vs_Saturating_Replete
- Navicula_pelliculosa_Saturating_Limiting_vs_Saturating_Replete
- Human_Blood_vs_Human_Plasma
- Human_Blood_vs_Human_Plasma
- Human_Blood_vs_Human_Plasma
- Inbreeding_Growth_Chamber_0_day_vs_Inbreeding_Growth_Chamber_92_day
- Blood_vs_Plasma
- Blood_vs_Plasma