Diff Profiles › MTBLS2945_0002_00000003

Control_vs_Lithogenic_Diet

Control vs Lithogenic Diet

p-value ≤ 0.05 246 significant 2025-09-26 00:00:00 Study: MTBLS2945
863 Total Features
246 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS2945_0002_00000003
Linked study
MTBLS2945 — Changes and correlations of intestinal flora and liver metabolite profiles in mice with gallstones
Comparison
Control vs Lithogenic Diet
Group A
Control group receiving a normal diet. Provides baseline data for comparison with the lithogenic diet group.
Group B
Test group receiving a lithogenic diet. Allows assessment of the impact of a lithogenic diet on the gut-liver axis.
Total features tested
863
Significant features
246
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
XPRWWANUPMYKMF-UUHDPGOWSA-N — up 99.76 2.12e-07
JVKYZPBMZPJNAJ-OQFNDJACSA-N (3β)-solanid-5-en-3-ol down 0.07144 2.85e-12
SREKYKXYSQMOIB-UHFFFAOYSA-N N-Carbamoylsarcosine down 2.877e-07 0.0183
BTCAEOLDEYPGGE-JVAZTMFWSA-N (3β,5α)-ergosta-7,24(28)-dien-3-ol up 31.87 6.14e-08
DNVPQKQSNYMLRS-APGDWVJJSA-N Provitamin D2 up 23.01 3.07e-08
MYWAIWDQTCHPTH-IUGQOUSLSA-N (3S,4S,10S,13R)-3-hydroxy-4,10,13-trimethyl-17-[(2S)-6-methylhept-5-en-2-yl]-1,2,3,5,6,7,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthrene-4-carboxylic acid up 10.66 1.61e-08
OTZRAYGBFWZKMX-FRFVZSDQSA-N (7E,9E,11Z,14Z)-(5S,6R)-6-(Cystein-S-yl)-5-hydroxyeicosa-7,9,11,14-tetraenoate down 0.03958 4.51e-06
HCXVJBMSMIARIN-PHZDYDNGSA-N Stigmasterol up 9.209 2.04e-08
RRTYEHFGQWNQKK-KIQAWMAPSA-N (5S,6Z,8E)-5-hydroxy-12-oxoicosa-6,8-dienoic acid up 10.32 7.71e-08
MYWAIWDQTCHPTH-YCIQJMEESA-N (3S,4S,5R,10S,13R)-3-hydroxy-4,10,13-trimethyl-17-[(2R)-6-methylhept-5-en-2-yl]-1,2,3,5,6,7,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthrene-4-carboxylic acid up 9.296 3.53e-07