Diff Profiles › MTBLS2945_0001_00000003

Control_vs_Lithogenic_Diet

Control vs Lithogenic Diet

p-value ≤ 0.05 131 significant 2025-09-26 00:00:00 Study: MTBLS2945
400 Total Features
131 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS2945_0001_00000003
Linked study
MTBLS2945 — Changes and correlations of intestinal flora and liver metabolite profiles in mice with gallstones
Comparison
Control vs Lithogenic Diet
Group A
Control group receiving a normal diet. Provides baseline data for comparison with the lithogenic diet group.
Group B
Test group receiving a lithogenic diet. Allows assessment of the impact of a lithogenic diet on the gut-liver axis.
Total features tested
400
Significant features
131
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
XBSQTYHEGZTYJE-OETIFKLTSA-N Lithocholic acid glycine conjugate up 2.367e+08 0.00183
GHCZAUBVMUEKKP-XROMFQGDSA-N GUDCA down 0.01015 5.83e-07
RUDATBOHQWOJDD-BSWAIDMHSA-N anthropodesoxycholic acid down 0.1029 8.77e-07
GIQXKAXWRLHLDD-VYACWCJYSA-N lithocholic acid 3-β-glucuronide up 6.413 6.09e-08
YLZRFVZUZIJABA-YFKPBYRVSA-N N-gamma-Acetyldiaminobutyrate down 0.04958 7.54e-05
RFDAIACWWDREDC-FRVQLJSFSA-N 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholan-24-oylglycine up 23.92 0.000142
MFYSYFVPBJMHGN-ZPOLXVRWSA-N 17alpha,21-Dihydroxy-4-pregnene-3,11,20-trione up 9.732 2.05e-05
MNLRQHMNZILYPY-MKFCKLDKSA-N N-Acetylmuramic acid down 0.1705 1.39e-06
UFPQIRYSPUYQHK-WAQVJNLQSA-N 5<i>S</i>,6<i>S</i>-epoxy-7<i>E</i>,9<i>E</i>,11<i>Z</i>,14<i>Z</i>-eicosatetraenoic acid up 5.384 8.4e-07
OEKUSRBIIZNLHZ-DJDNIQJZSA-N 3-ketocholic acid up 14.57 0.00103