Diff Profiles › MTBLS3927_0001_00000001

Sham_vs_Heart_Failure_Sedentary

Sham vs Heart Failure Sedentary

p-value ≤ 0.05 11 significant 2025-09-26 00:00:00 Study: MTBLS3927
134 Total Features
11 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS3927_0001_00000001
Linked study
MTBLS3927 — Exercise-generated β-aminoisobutyric acid (BAIBA) reduces cardiomyocytes metabolic stress and apoptosis caused by mitochondrial dysfunction through the miR-208b/AMPK pathway
Comparison
Sham vs Heart Failure Sedentary
Group A
Control group with no heart failure induction. Provides baseline for comparison with heart failure groups.
Group B
Heart failure group without exercise intervention. Serves as a comparison for exercise and BAIBA treatment effects.
Total features tested
134
Significant features
11
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
CQOVPNPJLQNMDC-ZETCQYMHSA-N (2<i>S</i>)-2-[(3-azaniumylpropanoyl)amino]-3-(1<em>H</em>-imidazol-4-yl)propanoate up 2.772 0.00183
OSJPPGNTCRNQQC-UWTATZPHSA-N 3-Phospho-D-glycerate up 2.691 0.00851
GXIURPTVHJPJLF-UHFFFAOYSA-N 3-hydroxy-2-(phosphonooxy)propanoic acid up 2.388 0.00557
MYYIAHXIVFADCU-QMMMGPOBSA-N beta-Alanyl-N(pai)-methyl-L-histidine up 2.439 0.00764
KFGOFTHODYBSGM-ZUNNJUQCSA-N 6-Oxoprostaglandin F1alpha down 0.3056 0.0382
CVSVTCORWBXHQV-UHFFFAOYSA-N {[amino(iminio)methyl](methyl)amino}acetate up 1.977 0.00662
WVIMUEUQJFPNDK-PEBGCTIMSA-N CDP ethanolamine up 1.642 0.00137
FNZLKVNUWIIPSJ-UHNVWZDZSA-N D-Ribulose 5-phosphate up 1.547 0.0125
NBAKTGXDIBVZOO-UHFFFAOYSA-N 5,6-Dihydro-5-methyluracil down 0.6436 0.0246
HXXFSFRBOHSIMQ-QTVWNMPRSA-N D-mannose 1-phosphates up 1.641 0.0422