Diff Profiles › MTBLS3927_0002_00000001

Sham_vs_Heart_Failure_Sedentary

Sham vs Heart Failure Sedentary

p-value ≤ 0.05 16 significant 2025-09-26 00:00:00 Study: MTBLS3927
196 Total Features
16 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS3927_0002_00000001
Linked study
MTBLS3927 — Exercise-generated β-aminoisobutyric acid (BAIBA) reduces cardiomyocytes metabolic stress and apoptosis caused by mitochondrial dysfunction through the miR-208b/AMPK pathway
Comparison
Sham vs Heart Failure Sedentary
Group A
Control group with no heart failure induction. Provides baseline for comparison with heart failure groups.
Group B
Heart failure group without exercise intervention. Serves as a comparison for exercise and BAIBA treatment effects.
Total features tested
196
Significant features
16
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
CQOVPNPJLQNMDC-ZETCQYMHSA-N (2<i>S</i>)-2-[(3-azaniumylpropanoyl)amino]-3-(1<em>H</em>-imidazol-4-yl)propanoate up 2.467 0.00039
FRJIAZKQGSCKPQ-FSPLSTOPSA-N Histidinoalanine up 2.32 0.000404
VZCCETWTMQHEPK-QNEBEIHSSA-N (6Z,9Z,12Z)-Octadecatrienoic acid up 3.097 0.00917
UYPYRKYUKCHHIB-UHFFFAOYSA-N TMAO up 2.537 0.00697
ASWBNKHCZGQVJV-HSZRJFAPSA-O 1-Palmitoylglycerophosphocholine up 2.081 0.00373
MYYIAHXIVFADCU-QMMMGPOBSA-N beta-Alanyl-N(pai)-methyl-L-histidine up 2.307 0.00748
HJCMDXDYPOUFDY-WHFBIAKZSA-N <small>L</small>-Ala-<small>L</small>-Gln up 1.628 0.00148
NHZMQXZHNVQTQA-UHFFFAOYSA-N 4-(AMINOMETHYL)-5-(HYDROXYMETHYL)-2-METHYLPYRIDIN-3-OL down 0.4986 0.0195
WVIMUEUQJFPNDK-PEBGCTIMSA-N CDP ethanolamine up 1.693 0.00768
DRCKHKZYDLJYFQ-YWIQKCBGSA-N isoleucylthreonine up 1.694 0.00952