Diff Profiles › MTBLS127_0003_00000002

HepG2_0uM_vs_HepG2_200uM

HepG2_0uM vs HepG2_200uM

p-value ≤ 0.05 39 significant 2025-09-26 00:00:00 Study: MTBLS127
79 Total Features
39 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS127_0003_00000002
Linked study
MTBLS127 — Resveratrol metabolism in HepG2 (human hepatocytes), HaCaT (human keratinocytes), and C2C12 (mouse myoblasts)
Comparison
HepG2_0uM vs HepG2_200uM
Group A
HepG2 cells with 0 µM Resveratrol. Baseline group for comparison with treated HepG2 samples.
Group B
HepG2 cells with 200 µM Resveratrol. Represents high concentration treatment effect in HepG2 cells.
Total features tested
79
Significant features
39
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
SSISHJJTAXXQAX-ZETCQYMHSA-N (α<i>S</i>)-α-carboxy-2,3-dihydro-<em>N</em>,<em>N</em>,<em>N</em>-trimethyl-2-thioxo-1<em>H</em>-imidazole-4-ethanaminium inner salt up 1e+06 2.78e-64
IGQBPDJNUXPEMT-UHFFFAOYSA-N 3-methylbutyrylcarnitine up 3 1.74e-65
XXEWFEBMSGLYBY-ZETCQYMHSA-N Lys(Me<small><sub>2</sub></small>) down 0.5 6.95e-63
XOHUEYCVLUUEJJ-UHFFFAOYSA-N 2,3-bis(phosphonooxy)propanoic acid up 2 6.95e-63
RFMMMVDNIPUKGG-YFKPBYRVSA-N (S)-2-(acetylamino)pentanedioic acid up 1e+06 0.00219
UHDGCWIWMRVCDJ-XVFCMESISA-N 4-amino-1-β-<small>D</small>-ribofuranosylpyrimidin-2(1<em>H</em>)-one down 0.07143 2.3e-05
RSPURTUNRHNVGF-IOSLPCCCSA-N 2-(dimethylamino)-9-(β-<small>D</small>-ribofuranosyl)-1,9-dihydro-6<em>H</em>-purin-6-one down 0.06667 0.000151
GHOKWGTUZJEAQD-UHFFFAOYSA-N <em>N</em>-(2,4-dihydroxy-3,3-dimethylbutanoyl)-β-alanine down 0.3463 4.19e-06
MVMSCBBUIHUTGJ-GDJBGNAASA-N Guanosine diphosphomannose down 0.2308 0.000157
HDYANYHVCAPMJV-LXQIFKJMSA-N UDP-alpha-D-glucuronate up 4.286 0.000382