ergothioneine

Metabolite details

Identifier: SSISHJJTAXXQAX-ZETCQYMHSA-N
InChI Key: SSISHJJTAXXQAX-ZETCQYMHSA-N
IUPAC name: (2S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trimethylazaniumyl)propanoate
Preferred name: ergothioneine
INN name: —
Synonym: (αS)-α-carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-1H-imidazole-4-ethanaminium inner salt
ChEBI: CHEBI:4828

Reactome pathways

No Reactome pathways listed for this metabolite.

Observed in studies

Distribution of RESV and its metabolite peaks in mouse tissues after oral and skin administration
Resveratrol metabolism in HepG2 (human hepatocytes), HaCaT (human keratinocytes), and C2C12 (mouse myoblasts)
Metabolomic Profile of Diet-Induced Obesity Mice in Response to Human and Small Humanin-like Peptide 2 Treatment
How Does the Seed Pre-germinative Metabolism Fight against Imbibition Damage; Emerging Roles of Fatty Acid Cohort and Antioxidant Defence
Human age-declined saliva metabolic markers determined by LC-MS
Red-Fleshed Apple Anthocyanin Extracts Attenuate Male Reproductive System Dysfunction Caused by Busulfan in Mice (Mouse blood plasma; UPLC-MS/MS assays)
Changes and correlations of intestinal flora and liver metabolite profiles in mice with gallstones
Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 21)
High complexity and diel dynamics of planktonic microbiome revealed by multi-omics in Taihu, China
Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 10)
Specific biomarkers for stochastic division patterns and starvation-induced quiescence under limited glucose levels in fission yeast
Transcriptional memory of dFOXO activation in youth curtails later-life mortality
Chronic sleep loss sensitizes Drosophila melanogaster to nitrogen stress
Distinct succinate modifying products are clinically diagnostic and prognostic biomarkers for fumarate hydratase deficient renal cell carcinoma
Mechanical force promotes dimethylarginine dimethylaminohydrolase 1-mediated hydrolysis of the metabolite asymmetric dimethylarginine to enhance bone formation
Exercise-generated β-aminoisobutyric acid (BAIBA) reduces cardiomyocytes metabolic stress and apoptosis caused by mitochondrial dysfunction through the miR-208b/AMPK pathway
Multi-omic Profiling of Multi-Biosamples Reveals the Role of Amino Acid and Nucleotide Metabolism in Endometrial Cancer
Metabolic profilings of rat INS-1 β-cells under changing levels of essential amino acids
Phosphoproteomic and Metabolomic Profiling Uncovers the Roles of CcPmk1 in the Pathogenicity of Cytospora chrysosperma
Integrated Metabolomics and Transcriptomics Analyses Reveal Anthocyanin and Carotenoid Biosynthesis Involved in Color Development in Willow Bark
Interaction between Cervical Microbiota and Host Gene Regulation in Caesarean Section Scar Diverticulum
Stage-specific roles of microbial dysbiosis and metabolic disorders in rheumatoid arthritis
Integrated Proteomic and Metabolomic Analyses Show Differential Effects of Glucose Availability in Marine Synechococcus and Prochlorococcus.
Diverse metabolic reactions activated during 58-hr fasting are revealed by non-targeted metabolomic analysis of human blood.
Flow cytometry has a significant impact on the cellular metabolome (Lipidomic LC-MS assay)
Metabolomic Analysis of Fission Yeast at the Onset of Nitrogen Starvation
PatA mediates biofilm formation and drugs resistance through regulating the synthesis of glycolipids and lipids in mycobacterium PatA mediates a novel mycolic acid synthesis pathway and regulates biofilm formation in mycobacterium
Metabolic changes associated with tick-microbe interactions
TGF-β uncouples glycolysis and inflammation in macrophages and controls the survival during sepsis
Genetic mapping and molecular mechanism behind color variation in the Asian vine snake
L-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS positive mode)
Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency.
Unexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites (Blood fraction)
Unexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites (Blood plasma and RBC fractions)

Metabolite details

Reactome pathways

Observed in studies

Observed in differential profiles