Resveratrol metabolism in HepG2 (human hepatocytes), HaCaT (human keratinocytes), and C2C12 (mouse myoblasts)

Study details

Source ID

https://identifiers.org/metabolights:MTBLS127

Title

Resveratrol metabolism in HepG2 (human hepatocytes), HaCaT (human keratinocytes), and C2C12 (mouse myoblasts)

Summary

Resveratrol metabolism in human and mouse cells.

Observation

Resveratrol metabolites and their tissue distribution after oral and skin absorption.

Findings

Glucuronidated metabolites more abundant in skin; RESV suppresses inflammation in TPA model.

Disease terms

inflammation

Gene terms

—

Chemical terms

polyphenol, dihydroresveratrol, resveratrol, RESV, Resveratrol

Organisms

humans, mouse

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS127.

{
  "@type": "Dataset",
  "integmet_study": "MTBLS127",
  "mesh_chemical_id": [
    "https://identifiers.org/mesh:D059808",
    "https://identifiers.org/mesh:C544754",
    "https://identifiers.org/mesh:D000077185"
  ],
  "mesh_chemical_pubtator_kw": [
    "polyphenol",
    "dihydroresveratrol",
    "resveratrol",
    "RESV",
    "Resveratrol"
  ],
  "mesh_disease_id": [
    "https://identifiers.org/mesh:D007249"
  ],
  "mesh_disease_pubtator_kw": [
    "inflammation"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:9606",
    "https://identifiers.org/taxonomy:10090"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "humans",
    "mouse"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS127",
  "study_findings": "Glucuronidated metabolites more abundant in skin; RESV suppresses inflammation in TPA model.",
  "study_observation": "Resveratrol metabolites and their tissue distribution after oral and skin absorption.",
  "study_summary": "Resveratrol metabolism in human and mouse cells.",
  "study_title_original": "Resveratrol metabolism in HepG2 (human hepatocytes), HaCaT (human keratinocytes), and C2C12 (mouse myoblasts)"
}