Diff Profiles › MTBLS7711_0001_00000003

SAR-S_vs_SAR-R

SAR-S vs SAR-R

p-value ≤ 0.05 75 significant 2025-09-26 00:00:00 Study: MTBLS7711
247 Total Features
75 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS7711_0001_00000003
Linked study
MTBLS7711 — L-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS positive mode)
Comparison
SAR-S vs SAR-R
Group A
Sarafloxacin-susceptible Salmonella Typhimurium samples. Baseline group for comparison with resistant samples.
Group B
Sarafloxacin-resistant Salmonella Typhimurium samples. Key group for understanding metabolic changes due to drug resistance.
Total features tested
247
Significant features
75
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
ILVGMCVCQBJPSH-WDSKDSINSA-N <small>L</small>-Ser-<small>L</small>-Val down 0.2452 3.66e-12
MDSUKZSLOATHMH-IUCAKERBSA-N <small>L</small>-Leu-<small>L</small>-Val up 27.38 1.55e-05
JQOHKCDMINQZRV-WDSKDSINSA-N <small>L</small>-Pro-<small>L</small>-Asn down 0.2451 7.16e-12
SSISHJJTAXXQAX-ZETCQYMHSA-N (α<i>S</i>)-α-carboxy-2,3-dihydro-<em>N</em>,<em>N</em>,<em>N</em>-trimethyl-2-thioxo-1<em>H</em>-imidazole-4-ethanaminium inner salt down 0.2635 7.92e-09
VHOLZZKNEBBHTH-YUMQZZPRSA-N histidylglutamic acid up 3.771 6.89e-08
JWBXCSQZLLIOCI-GUBZILKMSA-N <small>L</small>-Ile-<small>L</small>-Leu up 12.98 0.000253
KRNYOVHEKOBTEF-YUMQZZPRSA-N valylvaline up 8.113 4.19e-05
LZDNBBYBDGBADK-KBPBESRZSA-N V-W up 7.887 0.000195
IDXZDKMBEXLFMB-HGNGGELXSA-N H-I dipeptide up 6.325 9.62e-05
KTGFOCFYOZQVRJ-ZKWXMUAHSA-N I-E up 4.979 3.71e-05