Transcriptional memory of dFOXO activation in youth curtails later-life mortality

Study details

Source ID

https://identifiers.org/metabolights:MTBLS3251

Title

Transcriptional memory of dFOXO activation in youth curtails later-life mortality

Summary

dFOXO activation reduces later-life mortality in Drosophila.

Observation

dFOXO activation in early adulthood and its effects on longevity.

Findings

Early dFOXO activation reduces mortality via specific pathways and chromatin modifiers.

Disease terms

—

Gene terms

SWI, SNF, ISWI, Xbp1, dFOXO

Chemical terms

—

Organisms

flies

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS3251.

{
  "@type": "Dataset",
  "go_id": [
    "https://identifiers.org/GO:0006351",
    "https://identifiers.org/GO:0007568",
    "https://identifiers.org/GO:0016569"
  ],
  "go_kw": [
    "transcription",
    "ageing",
    "chromatin modification"
  ],
  "integmet_study": "MTBLS3251",
  "mesh_gene_id": [
    "https://identifiers.org/ncbigene:31120",
    "https://identifiers.org/ncbigene:31442",
    "https://identifiers.org/ncbigene:36390",
    "https://identifiers.org/ncbigene:44226",
    "https://identifiers.org/ncbigene:41709"
  ],
  "mesh_gene_pubtator_kw": [
    "SWI",
    "SNF",
    "ISWI",
    "Xbp1",
    "dFOXO"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:7147"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "flies"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS3251",
  "study_findings": "Early dFOXO activation reduces mortality via specific pathways and chromatin modifiers.",
  "study_observation": "dFOXO activation in early adulthood and its effects on longevity.",
  "study_summary": "dFOXO activation reduces later-life mortality in Drosophila.",
  "study_title_original": "Transcriptional memory of dFOXO activation in youth curtails later-life mortality"
}