The gut microbiome and metabolites are altered and interrelated in patients with rheumatoid arthritis

Study details

Source ID

https://identifiers.org/metabolights:MTBLS3233

Title

The gut microbiome and metabolites are altered and interrelated in patients with rheumatoid arthritis

Summary

Gut microbiome and metabolites in rheumatoid arthritis.

Observation

Gut microbiome and fecal metabolites in RA patients and healthy controls.

Findings

Altered genera and metabolites; Escherichia core genus; dysregulated metabolic pathways in RA.

Disease terms

RA, Rheumatoid Arthritis, rheumatoid arthritis

Gene terms

—

Chemical terms

lysoPC, tryptophan, L-arginine, PC, 3-hydroxyanthranilic acid, sphingolipids, aromatic amino acids, xanthurenic acid, glycerophospholipid, kynurenic acid, alpha-linolenic acid, glycerophospholipids

Organisms

Eisenbergiella, Enterococcus, Klebsiella, patients, Flavobacterium, Patients, Megamonas, Fusicatenibacter, Escherichia

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS3233.

{
  "@type": "Dataset",
  "go_id": [
    "https://identifiers.org/GO:0008152",
    "https://identifiers.org/GO:0006650",
    "https://identifiers.org/GO:0008652",
    "https://identifiers.org/GO:0009058",
    "https://identifiers.org/GO:0036109",
    "https://identifiers.org/GO:0006568"
  ],
  "go_kw": [
    "metabolism",
    "glycerophospholipid metabolism",
    "amino acid biosynthesis",
    "biosynthesis",
    "alpha-linolenic acid metabolism",
    "tryptophan metabolism"
  ],
  "integmet_study": "MTBLS3233",
  "mesh_chemical_id": [
    "https://identifiers.org/mesh:C006065",
    "https://identifiers.org/mesh:D014364",
    "https://identifiers.org/mesh:D001120",
    "https://identifiers.org/mesh:C053518",
    "https://identifiers.org/mesh:D015095",
    "https://identifiers.org/mesh:D013107",
    "https://identifiers.org/mesh:D024322",
    "https://identifiers.org/mesh:C028330",
    "https://identifiers.org/mesh:D020404",
    "https://identifiers.org/mesh:D007736",
    "https://identifiers.org/mesh:D017962"
  ],
  "mesh_chemical_pubtator_kw": [
    "lysoPC",
    "tryptophan",
    "L-arginine",
    "PC",
    "3-hydroxyanthranilic acid",
    "sphingolipids",
    "aromatic amino acids",
    "xanthurenic acid",
    "glycerophospholipid",
    "kynurenic acid",
    "alpha-linolenic acid",
    "glycerophospholipids"
  ],
  "mesh_disease_id": [
    "https://identifiers.org/mesh:D001172"
  ],
  "mesh_disease_pubtator_kw": [
    "RA",
    "Rheumatoid Arthritis",
    "rheumatoid arthritis"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:1432051",
    "https://identifiers.org/taxonomy:1350",
    "https://identifiers.org/taxonomy:570",
    "https://identifiers.org/taxonomy:9606",
    "https://identifiers.org/taxonomy:237",
    "https://identifiers.org/taxonomy:158846",
    "https://identifiers.org/taxonomy:1407607",
    "https://identifiers.org/taxonomy:562"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "Eisenbergiella",
    "Enterococcus",
    "Klebsiella",
    "patients",
    "Flavobacterium",
    "Patients",
    "Megamonas",
    "Fusicatenibacter",
    "Escherichia"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS3233",
  "study_findings": "Altered genera and metabolites; Escherichia core genus; dysregulated metabolic pathways in RA.",
  "study_observation": "Gut microbiome and fecal metabolites in RA patients and healthy controls.",
  "study_summary": "Gut microbiome and metabolites in rheumatoid arthritis.",
  "study_title_original": "The gut microbiome and metabolites are altered and interrelated in patients with rheumatoid arthritis"
}