Diff Profiles › MTBLS3233_0002_00000003

Rheumatoid_Arthritis_vs_Healthy_Control

Rheumatoid_Arthritis vs Healthy_Control

p-value ≤ 0.05 15 significant 2025-09-26 00:00:00 Study: MTBLS3233
76 Total Features
15 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS3233_0002_00000003
Linked study
MTBLS3233 — The gut microbiome and metabolites are altered and interrelated in patients with rheumatoid arthritis
Comparison
Rheumatoid_Arthritis vs Healthy_Control
Group A
Samples from untreated rheumatoid arthritis patients. Key group for understanding the metabolic and microbiome changes associated with rheumatoid arthritis
Group B
Samples from healthy control individuals. Provides a reference point for identifying disease-specific changes
Total features tested
76
Significant features
15
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
UHWYQXNZIBLESO-URLMMPGGSA-N C12:0 DHCer down 0.4289 2.13e-13
UDTSZXVRDXQARY-IOWSJCHKSA-N DHC-A 18:0/14:0 down 0.3926 5.8e-10
OCRUDDLKDFDNGT-GJZGRUSLSA-N N-[(1S,2R)-2,3-dihydroxy-1-phenylpropyl]benzamide up 6.06 0.0309
ASUSBMNYRHGZIG-UHFFFAOYSA-N N-Methylserotonin down 0.2731 0.00879
NBYLBWHHTUWMER-UHFFFAOYSA-N 2-methylquinolin-8-ol down 0.259 0.015
QRMPRVXWPCLVNI-YYFQZIEXSA-N (1S,2S,5S,8R,9S)-2-methyl-6-methylidene-9-propan-2-yl-11-oxatricyclo[6.2.1.01,5]undecan-8-ol down 0.2676 0.0183
VLPIATFUUWWMKC-UHFFFAOYSA-N Mexiletine up 3.574 0.0208
AUFJTVGCSJNQIF-UHFFFAOYSA-N 2-amino-4-hydroxy-1H-pyrimidin-6-one down 0.2515 0.029
ZXZKYYHTWHJHFT-UHFFFAOYSA-N Quinolin-2,8-diol down 0.3464 0.0122
PMZDQRJGMBOQBF-UHFFFAOYSA-N Quinolin-4-ol down 0.2443 0.0457