Control_vs_TGF-beta_Treatment

Control vs TGF-beta_Treatment

p-value ≤ 0.05 33 significant 2025-09-26 00:00:00 Study: MTBLS6886
107 Total Features
33 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS6886_0003_00000001
Linked study
MTBLS6886 — TGF-β uncouples glycolysis and inflammation in macrophages and controls the survival during sepsis
Comparison
Control vs TGF-beta_Treatment
Group A
Macrophages treated with control conditions. Provides baseline data for comparison with TGF-beta treated samples
Group B
Macrophages treated with TGF-beta. Key group for assessing the impact of TGF-beta on macrophage metabolism
Total features tested
107
Significant features
33
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
DRBBFCLWYRJSJZ-UHFFFAOYSA-N N-phosphocreatine up 4.178 1.3e-05
XZKQVQKUZMAADP-IMJSIDKUSA-N S-S up 3.194 0.00299
CQOVPNPJLQNMDC-ZETCQYMHSA-N (2<i>S</i>)-2-[(3-azaniumylpropanoyl)amino]-3-(1<em>H</em>-imidazol-4-yl)propanoate up 2.371 0.000474
HJCMDXDYPOUFDY-WHFBIAKZSA-N <small>L</small>-Ala-<small>L</small>-Gln up 4.058 0.00953
NCMVOABPESMRCP-SHYZEUOFSA-N Deoxycytidylate up 2.219 0.000526
UTAIYTHAJQNQDW-KQYNXXCUSA-N N1-Methylguanosine up 3.8 0.0117
OUYCCCASQSFEME-QMMMGPOBSA-N (2<i>S</i>)-2-ammonio-3-(4-hydroxyphenyl)propanoate up 2.326 0.000931
PYUSHNKNPOHWEZ-YFKPBYRVSA-N N-formylmethionine down 0.4089 0.00203
VSNFQQXVMPSASB-SNVBAGLBSA-O down 0.6131 2.18e-05
ZNXZGRMVNNHPCA-VIFPVBQESA-N Pantetheine up 3.075 0.0101