Metabolite details
Reactome pathways
- R-HSA-1430728 - Metabolism
- R-HSA-1643685 - Disease
- R-HSA-209776 - Metabolism of amine-derived hormones
- R-HSA-209905 - Catecholamine biosynthesis
- R-HSA-209968 - Thyroxine biosynthesis
- R-HSA-352230 - Amino acid transport across the plasma membrane
- R-HSA-379716 - Cytosolic tRNA aminoacylation
- R-HSA-379724 - tRNA Aminoacylation
- R-HSA-379726 - Mitochondrial tRNA aminoacylation
- R-HSA-382551 - Transport of small molecules
- R-HSA-392499 - Metabolism of proteins
- R-HSA-425407 - SLC-mediated transmembrane transport
- R-HSA-442660 - SLC-mediated transport of neurotransmitters
- R-HSA-5619044 - Defective SLC6A19 causes Hartnup disorder (HND)
- R-HSA-5619102 - SLC transporter disorders
- R-HSA-5619115 - Disorders of transmembrane transporters
- R-HSA-5659735 - Defective SLC6A19 causes Hartnup disorder (HND)
- R-HSA-5662702 - Melanin biosynthesis
- R-HSA-597592 - Post-translational protein modification
- R-HSA-71240 - Tryptophan catabolism
- R-HSA-71291 - Metabolism of amino acids and derivatives
- R-HSA-72766 - Translation
- R-HSA-8955332 - Carboxyterminal post-translational modifications of tubulin
- R-HSA-8963684 - Tyrosine catabolism
- R-HSA-8963691 - Phenylalanine and tyrosine metabolism
- R-HSA-8964208 - Phenylalanine metabolism
- R-HSA-9958863 - SLC-mediated transport of amino acids
Observed in studies
- Biological effect of chronic mistranslation in mammalian cells
- Cell-based and multi-omics profiling reveal dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei
- Metabolome analysis via an HPLC-ESI-MS-based experimental and computational pipeline for chronic nephron toxicity profiling
- Metabolic cooperation and spatiotemporal niche partitioning in a kefir microbial community; Interaction between the kefir isolates Lactococcus lactis and Acetobacter fabarum (GC-MS)
- A metabolite roadmap of the wood-forming tissue in Populus tremula (UPLC-MS assay; Wood fibre and ray cell tissue)
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Escherichia coli assays)
- The response of Chlamydomonas reinhardtii to nitrogen deprivation: a systems biology analysis
- Metabolic Dynamics of In Vitro CD8+ T Cell Activation.
- Global analysis of plasma lipidomics reveals altered lipid signatures in patients with osteonecrosis of the femoral head
- Model-driven multi-omic data analysis elucidates metabolic immunomodulators of macrophage activation
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Klebsiella pneumoniae assays)
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Streptococcus pneumoniae assays)
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Streptococcus pyogenes assays)
- Multi-Omics Analysis Reveals Disturbance of Nanosecond Pulsed Electric Field in the Serum Metabolic Spectrum and Gut Microbiota
- Integrated Analyses of the Gut Microbiota, Intestinal Permeability and Serum Metabolome Phenotype in Rats with Alcohol Withdrawal Syndrome
- Fat Deposition in the Muscle of Female and Male Yak and the Correlation of Yak Meat Quality with Fat
- Red-Fleshed Apple Anthocyanin Extracts Attenuate Male Reproductive System Dysfunction Caused by Busulfan in Mice (Mouse blood plasma; UPLC-MS/MS assays)
- Metabolic characterization of the natural progression of chronic hepatitis B (Biogenic amine and Acyl-carnitine assays).
- SARS-CoV-2-reprogrammed metabolism and autophagy reduction uncover host-targeting antivirals
- Metabolites from surface seawater collected in Narragansett Bay
- Changes and correlations of intestinal flora and liver metabolite profiles in mice with gallstones
- Distinct metabolic profiling is correlated with bisexual flowers formation resulting from exogenous ethephon induction in melon (<i>Cucumis melo</i> L.)
- Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 21)
- Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 10)
- Multiple biochemical indices and metabolomics of Clonorchis sinensis provide a novel interpretation of biomarkers
- Plant elicitor peptide signalling confers rice resistance to piercing-sucking insect herbivores and pathogens
- Analysis of Growth Phases of Enterotoxigenic Escherichia coli Reveals a Distinct Transition Phase before Entry into Early Stationary Phase with Shifts in Tryptophan, Fucose, and Putrescine Metabolism and Degradation of Neurotransmitter Precursors
- Distinct succinate modifying products are clinically diagnostic and prognostic biomarkers for fumarate hydratase deficient renal cell carcinoma
- Gut microbiome drives individual memory variation in bumblebees
- The Manchurian Walnut Genome: Insights into Juglone and Lipid Biosynthesis.
- Diallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice
- Appropriate taxonomic classification of intestinal microbiome by 16S rRNA gene targeting metagenomic approach
- Chromosome‐level genome of
- Exercise-generated β-aminoisobutyric acid (BAIBA) reduces cardiomyocytes metabolic stress and apoptosis caused by mitochondrial dysfunction through the miR-208b/AMPK pathway
- Multi-omic Profiling of Multi-Biosamples Reveals the Role of Amino Acid and Nucleotide Metabolism in Endometrial Cancer
- Metabolic profilings of rat INS-1 β-cells under changing levels of essential amino acids
- Characterization of white tea metabolome: comparison against green and black tea by a nontargeted metabolomics approach.
- Transcriptional Shift and Metabolic Adaptations during Leishmania Quiescence Using Stationary Phase and Drug Pressure as Models
- Proteomic and metabolic changes in cancer cells after alternation of SHMT2 expressions
- Transcriptome and Metabolome Analyses Reveal Differences in Terpenoid and Flavonoid Biosynthesis in Cryptomeria fortunei Needles Across Different Seasons
- Effects of Radiofrequency Field from 5G Communications on fecal microbiome and metabolome profiles in mice
- Novel Potential Diagnostic Serum Biomarkers of Metabolomics in Osteoarticular Tuberculosis Patients: A Preliminary Study
- Homeostasis of the biosynthetic E. coli metabolome
- Mining for metabolic responses to long-term salt stress: a case study on the model legume Lotus japonicus (A)
- The Genome of Medicinal Plant Macleaya cordata Provides New Insights into Benzylisoquinoline Alkaloids Metabolism
- Seed Metabolome Analysis of a Transgenic Rice Line Expressing Cholera Toxin B-subunit
- Phosphoproteomic and Metabolomic Profiling Uncovers the Roles of CcPmk1 in the Pathogenicity of <i>Cytospora chrysosperma</i>
- Cardiac disruption of SDHAF4-mediated mitochondrial complex II assembly promotes dilated cardiomyopathy.
- Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors
- Integrated Metabolomics and Transcriptomics Analyses Reveal Anthocyanin and Carotenoid Biosynthesis Involved in Color Development in Willow Bark
- Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Feces metabolomics)
- Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Brain tissue metabolomics)
- Sodium Butyrate mediates Histone Crotonylation and Alleviated Neonatal Rats Hypoxic-Ischemic Brain Injury Through Gut-Brain Axis (untargeted fecal metabolomics)
- Interaction between Cervical Microbiota and Host Gene Regulation in Caesarean Section Scar Diverticulum
- Mechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis
- Inorganic Carbon Limitation in Cells of the Wild Type and Photorespiratory Mutants of the Cyanobacterium Synechocystis sp. Strain PCC 6803
- Multiomic analysis revealed the potential role of rumen microbes in heat stress
- Effect of heat stress on serum enzyme activity, antioxidant capacity and immune parameter metabolomics datasets in Holstein cows at different growth stages
- Stage-specific roles of microbial dysbiosis and metabolic disorders in rheumatoid arthritis
- Mining for metabolic responses to long-term salt stress: a case study on the model legume Lotus japonicus (C)
- Bile acid is a significant host factor shaping the gut microbiome of diet induced obese mice (untargeted metabolome profile assay)
- Metabolic disorder and intestinal microflora dysbiosis in chronic inflammatory demyelinating polyradiculoneuropathy
- DNA-PKcs drives CKD progression by activating TAF7/RAPTOR/mTORC1 signaling-mediated metabolic reprogramming
- GABA regulates IL-1β production in macrophages
- FSCN1 as a new druggable target in adrenocortical carcinoma
- Transcriptomics and metabolomics analysis reveal the anti-oxidation and immune boosting effects of mulberry leaves in growing mutton sheep
- Extracellular-acidosis restricts one-carbon metabolism and preserves T cell stemness
- PatA mediates biofilm formation and drugs resistance through regulating the synthesis of glycolipids and lipids in mycobacterium PatA mediates a novel mycolic acid synthesis pathway and regulates biofilm formation in mycobacterium
- TGF-β uncouples glycolysis and inflammation in macrophages and controls the survival during sepsis
- Unraveling the metabolic effects of benzophenone-3 on the endosymbiotic dinoflagellate Cladocopium goreaui
- Genetic mapping and molecular mechanism behind color variation in the Asian vine snake
- Metabolic consequences of cobalamin scarcity in diatoms as revealed through metabolomics (Thalassiosira pseudonana study)
- Metabolic consequences of cobalamin scarcity in diatoms as revealed through metabolomics (Navicula pelliculosa study)
- Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice
- Integrated Proteomics and Metabolomics Analysis Reveals Differential Lipid Metabolism in HUVEC under high and low shear stress
- Disturbed Microbiota-Metabolites-Immune Interaction Network is Associated with Olfactory Dysfunction in Patients with Chronic Rhinosinusitis
- L-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS positive mode)
- L-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS negative mode)
- Plasma metabolite changes in dairy cows during parturition identified using untargeted metabolomics.
- Changing environments and genetic variation: inbreeding does not compromise short-term physiological responses
Observed in differential profiles
- rps2_wildtype_vs_rps2_A226Y
- Non_Induced_0_Day_vs_Induced_8_Day
- Non_Induced_0_Day_vs_Induced_8_Day
- Control_1_day_vs_High_14_day
- Control_1_day_vs_High_14_day
- Milk_0h_vs_Whey_72h
- Fiber_vs_Ray
- RPMI_B36_vs_Pooled_Sera_B36
- RPMI_B36_vs_Pooled_Sera_B36
- 0h_vs_24h
- G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
- G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
- Control_vs_AONFH_Stage_III_IV
- G1_Klebsiella_pneumoniae_AJ218_RPMI_vs_G2_Klebsiella_pneumoniae_AJ218_Pooled_sera
- G1_Klebsiella_pneumoniae_AJ218_RPMI_vs_G2_Klebsiella_pneumoniae_AJ218_Pooled_sera
- G1_Pooled_Sera_Blood_4559_vs_G2_RPMI_Glucose_Blood_4559
- G1_RPMI_modified_Blood_M1T1_5448_vs_G2_Pooled_sera_Blood_M1T1_5448
- G1_RPMI_modified_Blood_M1T1_5448_vs_G2_Pooled_sera_Blood_M1T1_5448
- Control_vs_Lipopolysaccharide_stimulated
- Control_vs_nsPEF_7_day
- Alcohol_Treatment_vs_Control
- Male_vs_Female
- Control_vs_Busulfan_5_mg_kg_RAAE
- Control_vs_Immune_Tolerant
- Control_vs_Immune_Tolerant
- Control_vs_Immune_Tolerant
- Calu3_Mock_DMEM_vs_Calu3_10uM_NIC
- 16_May_2012_vs_8_June_2012
- Control_vs_Lithogenic_Diet
- Control_vs_Ethephon_Treatment
- Sham_vs_UIR
- Sham_vs_UIR
- Control_14dpi_vs_Infected_14dpi
- ZH11_Mock_vs_ZH11_OsPep3
- E1777_Intracellular_MidLog_vs_E1777_Intracellular_EarlyStationary
- Normal_control_no_tumor_vs_FH_deficient_RCC
- Hindgut_Control_vs_Lactobacillus_apis
- Embryo_S1_vs_Embryo_S4
- G1_PBS_vs_G2_DSS
- Flower_vs_Kernel
- Untreated_vs_Antibiotic_Treated
- Untreated_vs_Antibiotic_Treated
- Sham_vs_Heart_Failure_Sedentary
- Control_vs_Endometrial_Cancer
- G1_Control_vs_G2_Arginine_Addition
- White_Tea_0h_vs_White_Tea_36h
- AMAD_Log_vs_AMAE_Sta
- Control_No_Glycine_vs_SHMT2_Upregulated_No_Glycine
- Control_No_Glycine_vs_SHMT2_Upregulated_No_Glycine
- Summer_vs_Winter
- Summer_vs_Winter
- Sham_vs_Radiofrequency
- Healthy_Control_vs_Osteoarticular_Tuberculosis
- Glu_BW25113_vs_Pyr_BW25113
- Labeled_Leaf_vs_Unlabeled_Leaf
- Labeled_Leaf_vs_Unlabeled_Leaf
- MR-CTB51A_vs_NPB-HP
- Control_vs_150mM
- CcPmk1_vs_Wild_type
- Wild_type_vs_Knock_out
- Wild_Type_vs_Gene_Knockout
- Purple_vs_Green
- Normal_vs_Neural_Tube_Defect
- Normal_vs_Neural_Tube_Defect
- Sham_vs_HIBD
- Control_vs_CSD
- Control_vs_ZYP_High_Dose
- Dc-N_vs_Dc-HS
- Dcs_N_vs_Dcs_HS
- Healthy_vs_RAS4
- Normal_Diet_vs_High-fat_Diet
- Normal_Diet_vs_High-fat_Diet
- Normal_Diet_vs_High-fat_Diet
- Control_vs_150mM
- CIDP_patient_vs_healthy_control
- DNA-PK_KO_UUO_vs_DNA-PK_KO_Control
- WT_vs_sll0404.ko
- Control_0h_vs_GABA_0h
- Control_Vehicle_vs_FSCN1_Knockout_Vehicle
- Control_vs_Fermented_Mulberry_Leaves
- Control_vs_Lactic_Acid
- wild_type_vs_patA_deletion
- Control_vs_TGF-beta_Treatment
- Control_vs_BP3_Low_Concentration
- Yellow_Skin_vs_Green_Skin
- Saturating_Limiting_vs_Saturating_Replete
- Navicula_pelliculosa_Saturating_Limiting_vs_Saturating_Replete
- Navicula_pelliculosa_Saturating_Limiting_vs_Saturating_Replete
- ASD_Fecal_vs_TD_Fecal
- Low_Shear_Stress_vs_High_Shear_Stress
- Normal_vs_Abnormal
- SAR-S_vs_SAR-R
- SAR-R_vs_SAR-S
- After_Calving_vs_21_Days_Before_Due_Date
- Inbreeding_Growth_Chamber_0_day_vs_Inbreeding_Growth_Chamber_92_day