Wild_type_vs_Knock_out

Wild type vs Knock-out

p-value ≤ 0.05 23 significant 2025-09-26 00:00:00 Study: MTBLS4579
133 Total Features
23 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS4579_0001_00000001
Linked study
MTBLS4579 — Cardiac disruption of SDHAF4-mediated mitochondrial complex II assembly promotes dilated cardiomyopathy.
Comparison
Wild type vs Knock-out
Group A
Wild type mice samples from the left ventricle.. Serves as the control group for evaluating the effects of Sdhaf4 knock-out.
Group B
Knock-out mice samples from the left ventricle.. Allows for the assessment of the impact of Sdhaf4 knock-out on cardiac function.
Total features tested
133
Significant features
23
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
YNYAYWLBAHXHLL-UHFFFAOYSA-N 3-Methoxy-Noradrenaline up 3.638 7.39e-06
RGHNJXZEOKUKBD-SQOUGZDYSA-N Hexonic acid down 0.2763 0.000176
MPCAJMNYNOGXPB-SLPGGIOYSA-N 1,5-Anhydro-D-sorbitol down 0.2951 0.000144
KDXKERNSBIXSRK-YFKPBYRVSA-N L-Lysine up 2.521 3.51e-05
WQZGKKKJIJFFOK-HOWGCPQDSA-N L-allopyranose down 0.4582 6.9e-06
GHBFNMLVSPCDGN-UHFFFAOYSA-N Glyceryl 1-monooctanoate down 0.4364 0.000287
KKADPXVIOXHVKN-UHFFFAOYSA-N 3-(4-HYDROXY-PHENYL)PYRUVIC ACID down 0.3824 0.00161
ODKSFYDXXFIFQN-BYPYZUCNSA-N (2<i>S</i>)-2-amino-5-guanidinopentanoic acid up 2.412 0.00101
BTCSSZJGUNDROE-UHFFFAOYSA-N GABA up 2.403 0.0013
YWWVWXASSLXJHU-WAYWQWQTSA-N Myristoleic acid up 2.115 0.00128