Sham_vs_HIBD — integMET

Profile details

Identifier: MTBLS4932_0001_00000005
Linked study: MTBLS4932 — Sodium Butyrate mediates Histone Crotonylation and Alleviated Neonatal Rats Hypoxic-Ischemic Brain Injury Through Gut-Brain Axis (untargeted fecal metabolomics)
Comparison: Sham vs HIBD
Group A: Sham control group. Provides a baseline for comparing the effects of HIBD and the intervention.
Group B: Neonatal hypoxic-ischemic brain damage group. Key group for understanding the baseline effects of HIBD.
Total features tested: 310
Significant features: 129
p-value threshold: 0.05
Ratio threshold (upper): 1.5
Ratio threshold (lower): 1/1.5
Date created: 2025-09-26 00:00:00

Metabolite ID (InChI Key)	Name	Direction	Ratio	p-value
KDYFGRWQOYBRFD-UHFFFAOYSA-N	E363	down	0.09757	1.18e-10
FUZZWVXGSFPDMH-UHFFFAOYSA-N	HEXANOIC ACID	down	0.01719	6.14e-05
WHBMMWSBFZVSSR-GSVOUGTGSA-N	(R)-3-Hydroxybutyric acid	down	0.1079	7.6e-08
XQXPVVBIMDBYFF-UHFFFAOYSA-N	4-Hydroxyphenylacetic acid	down	0.2315	4.26e-11
JVTAAEKCZFNVCJ-REOHCLBHSA-N	L-Lactic acid	up	4.786	2.04e-08
RGHNJXZEOKUKBD-SQOUGZDYSA-N	Hexonic acid	up	5.412	8.2e-08
WLJVXDMOQOGPHL-UHFFFAOYSA-N	benzeneacetic acid	down	0.1963	7.76e-08
NQPDZGIKBAWPEJ-UHFFFAOYSA-N	n-Valeric acid	down	0.1548	7.5e-07
COCMFMBNEAMQMA-VGKGADPCSA-N	(4R)-4-[(3R,5R,6S,7S,8R,9S,10R,12S,13R,14S,17R)-3,6,7,12-tetrahydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid	down	0.02827	0.000756
GFFGJBXGBJISGV-UHFFFAOYSA-N	Adenin	up	5.902	1.03e-06