Metabolite details
Reactome pathways
- R-HSA-110331 - Cleavage of the damaged purine
- R-HSA-1237112 - Methionine salvage pathway
- R-HSA-1430728 - Metabolism
- R-HSA-15869 - Metabolism of nucleotides
- R-HSA-1614635 - Sulfur amino acid metabolism
- R-HSA-1643685 - Disease
- R-HSA-382551 - Transport of small molecules
- R-HSA-425397 - Transport of vitamins, nucleosides, and related molecules
- R-HSA-425407 - SLC-mediated transmembrane transport
- R-HSA-5619063 - Defective SLC29A3 causes histiocytosis-lymphadenopathy plus syndrome (HLAS)
- R-HSA-5619102 - SLC transporter disorders
- R-HSA-5619115 - Disorders of transmembrane transporters
- R-HSA-5668914 - Diseases of metabolism
- R-HSA-71291 - Metabolism of amino acids and derivatives
- R-HSA-73884 - Base Excision Repair
- R-HSA-73894 - DNA Repair
- R-HSA-73927 - Depurination
- R-HSA-73929 - Base-Excision Repair, AP Site Formation
- R-HSA-74217 - Purine salvage
- R-HSA-83936 - Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
- R-HSA-8956321 - Nucleotide salvage
- R-HSA-9734195 - Defective APRT disrupts adenine salvage
- R-HSA-9734207 - Nucleotide salvage defects
- R-HSA-9735804 - Diseases of nucleotide metabolism
Observed in studies
- Biological effect of chronic mistranslation in mammalian cells
- Absence of tmRNA Increases the Persistence to Cefotaxime and the Intercellular Accumulation of Metabolite GlcNAc in <i>Aeromonas veronii</i>.
- Absence of tmRNA increases the persistence to cefotaxime by upregulating the metabolites GlcNAc in Aeromonas veronii
- Distribution of RESV and its metabolite peaks in mouse tissues after oral and skin administration
- Resveratrol metabolism in HepG2 (human hepatocytes), HaCaT (human keratinocytes), and C2C12 (mouse myoblasts)
- Cell-based and multi-omics profiling reveal dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei
- Hfq Regulates Efflux Pump Expression and Purine Metabolic Pathway to Increase the Trimethoprim Resistance in Aeromonas veronii
- Metabolomics analysis identifies metabolites associated with systemic acquired resistance in Arabidopsis
- Metabolomic Profile of Diet-Induced Obesity Mice in Response to Human and Small Humanin-like Peptide 2 Treatment
- Four layer multi-omics reveals molecular responses to aneuploidy in <i>Leishmania</i>
- Jejunal inflammatory cytokines, barrier proteins and microbiome-metabolome responses to early supplementary feeding of Bamei suckling piglets
- Bioaccumulation of therapeutic drugs by human gut bacteria: cross-feeding metabolite analysis (FIA-MS) (E.rectale;S.salivarius assays)
- How Does the Seed Pre-germinative Metabolism Fight against Imbibition Damage; Emerging Roles of Fatty Acid Cohort and Antioxidant Defence
- The impact of slyA on cell metabolism of Salmonella Typhimurium: a joint study of transcriptomics and
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Escherichia coli assays)
- Human age-declined saliva metabolic markers determined by LC-MS
- Metabolic Dynamics of In Vitro CD8+ T Cell Activation.
- Metabolomic profiling reveals the effects of early-life lactoferrin intervention on protein synthesis, energy production and antioxidative capacity in the liver of suckling piglets
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Klebsiella pneumoniae assays)
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Streptococcus pneumoniae assays)
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Streptococcus pyogenes assays)
- Transcriptional differentiation of Trypanosoma brucei during in vitro acquisition of resistance to acoziborole
- Metabolic Dynamics in <i>Escherichia coli</i>-Based Cell-Free Systems
- Host autophagy mediates organ wasting and nutrient mobilization for tumor growth.
- Transcriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth
- Microbial Diversity and Non-volatile Metabolites Profile of Low-Temperature Sausage Stored at Room Temperature
- Dietary carbohydrate and protein levels affect the growth performance of juvenile peanut worm (Sipunculus nudus): an LC–MS-based metabolomics study
- Metabolites from surface seawater collected in Narragansett Bay
- A Phosphate starvation response gene (psr1-like) is present in Micromonas pusilla and other marine algae and coordinates the metabolic response to phosphate deficiency
- Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 21)
- Metabolomics dataset of PPAR-pan treated rat liver (acyl-carnitine and aqueous metabolite assays)
- High complexity and diel dynamics of planktonic microbiome revealed by multi-omics in Taihu, China
- Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 10)
- Jasmonate-mediated stomatal closure under elevated CO2 revealed by time-resolved metabolomics
- Multiple biochemical indices and metabolomics of Clonorchis sinensis provide a novel interpretation of biomarkers
- Chronic sleep loss sensitizes Drosophila melanogaster to nitrogen stress
- Plant elicitor peptide signalling confers rice resistance to piercing-sucking insect herbivores and pathogens
- Metabolite profile data of grapevine plants with brown wood streaking and grapevine leaf stripe (esca complex disease) symptoms
- Analysis of Growth Phases of Enterotoxigenic Escherichia coli Reveals a Distinct Transition Phase before Entry into Early Stationary Phase with Shifts in Tryptophan, Fucose, and Putrescine Metabolism and Degradation of Neurotransmitter Precursors
- Metabolomics and lipidomics reveal perturbation of sphingolipid metabolism by a novel anti-trypanosomal 3-(oxazolo[4,5-b]pyridine-2-yl)anilide
- Distinct succinate modifying products are clinically diagnostic and prognostic biomarkers for fumarate hydratase deficient renal cell carcinoma
- Gut microbiome drives individual memory variation in bumblebees
- The Manchurian Walnut Genome: Insights into Juglone and Lipid Biosynthesis.
- Metabolic signatures of Arabidopsis thaliana abiotic stress responses elucidate patterns in stress priming, acclimation, and recovery
- Evaluation of algorithms for multiple alignment of GCxGC-MS data
- Appropriate taxonomic classification of intestinal microbiome by 16S rRNA gene targeting metagenomic approach
- Exercise-generated β-aminoisobutyric acid (BAIBA) reduces cardiomyocytes metabolic stress and apoptosis caused by mitochondrial dysfunction through the miR-208b/AMPK pathway
- Multi-omic Profiling of Multi-Biosamples Reveals the Role of Amino Acid and Nucleotide Metabolism in Endometrial Cancer
- A Combined Proteomic and Metabolomic Strategy for Allergens Characterization in Natural and Fermented <em>Brassica napus</em> Bee Pollen
- Metabolic profilings of rat INS-1 β-cells under changing levels of essential amino acids
- Effects of Radiofrequency Field from 5G Communications on fecal microbiome and metabolome profiles in mice
- Homeostasis of the biosynthetic E. coli metabolome
- Comparative Metabolomic Profiling of Compatible and Incompatible Interactions Between Potato and Phytophthora infestans
- Cardiac disruption of SDHAF4-mediated mitochondrial complex II assembly promotes dilated cardiomyopathy.
- Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors
- Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Feces metabolomics)
- Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Brain tissue metabolomics)
- Sodium Butyrate mediates Histone Crotonylation and Alleviated Neonatal Rats Hypoxic-Ischemic Brain Injury Through Gut-Brain Axis (untargeted fecal metabolomics)
- Mechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis
- Inorganic Carbon Limitation in Cells of the Wild Type and Photorespiratory Mutants of the Cyanobacterium Synechocystis sp. Strain PCC 6803
- Multiomic analysis revealed the potential role of rumen microbes in heat stress
- Effect of heat stress on serum enzyme activity, antioxidant capacity and immune parameter metabolomics datasets in Holstein cows at different growth stages
- Transcriptomic dynamics control rapid transition of core crop functions in 'lactating' pigeon
- PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis.
- Bile acid is a significant host factor shaping the gut microbiome of diet induced obese mice (untargeted metabolome profile assay)
- Integrated Proteomic and Metabolomic Analyses Show Differential Effects of Glucose Availability in Marine <i>Synechococcus</i> and <i>Prochlorococcus</i>.
- Diverse metabolic reactions activated during 58-hr fasting are revealed by non-targeted metabolomic analysis of human blood.
- DNA-PKcs drives CKD progression by activating TAF7/RAPTOR/mTORC1 signaling-mediated metabolic reprogramming
- GABA regulates IL-1β production in macrophages
- FSCN1 as a new druggable target in adrenocortical carcinoma
- Transcriptomics and metabolomics analysis reveal the anti-oxidation and immune boosting effects of mulberry leaves in growing mutton sheep
- A Pilot Characterization of the Human Chronobiome
- Comparative metabolomic analysis of exudates of microcystin-producing and microcystin-free Microcystis aeruginosa strains
- Extracellular-acidosis restricts one-carbon metabolism and preserves T cell stemness
- Metabolomic Analysis of Fission Yeast at the Onset of Nitrogen Starvation
- PatA mediates biofilm formation and drugs resistance through regulating the synthesis of glycolipids and lipids in mycobacterium PatA mediates a novel mycolic acid synthesis pathway and regulates biofilm formation in mycobacterium
- Metabolic changes associated with tick-microbe interactions
- Unraveling the metabolic effects of benzophenone-3 on the endosymbiotic dinoflagellate Cladocopium goreaui
- Genetic mapping and molecular mechanism behind color variation in the Asian vine snake
- Bacterial Pathogens Hijack the Innate Immune Response by Activation of the Reverse Transsulfuration Pathway.
- Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice
- Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction
- L-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS positive mode)
- L-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS negative mode)
- Metabolic effects of an aspartate aminotransferase-inhibitor on two T-cell lines
- Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency.
- Inhibition of glycolysis and mitochondrial respiration promotes radiosensitisation of neuroblastoma and glioma cells
- Unexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites (Blood fraction)
- Unexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites (Blood plasma and RBC fractions)
- Changing environments and genetic variation: inbreeding does not compromise short-term physiological responses
Observed in differential profiles
- rps2_wildtype_vs_rps2_A226Y
- Wild_Type_vs_tmRNA_Deletion
- Wild_Type_vs_tmRNA_Knockout
- Wild_Type_vs_tmRNA_Knockout
- Control_Oral_Blood_vs_RESV_Oral_Blood
- Control_Oral_Blood_vs_RESV_Oral_Blood
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- Non_Induced_0_Day_vs_Induced_8_Day
- Non_Induced_0_Day_vs_Induced_8_Day
- Wild_type_vs_hfq
- Wild_type_vs_hfq
- Local_Leaf_Control_vs_Local_Leaf_Avr
- Water_vs_HNG
- Water_vs_HNG
- Water_vs_HNG
- Water_vs_HNG
- Nepalese_BPK173_vs_Nepalese_BPK178
- Supplementary_feeding_vs_Control
- G4_Eubacterium_rectale_DMSO_30_vs_G3_Eubacterium_rectale_Duloxetine_47
- Dry_Seed_vs_8h_Imbibed_Seed
- slyA_vs_wild_type
- RPMI_B36_vs_Pooled_Sera_B36
- RPMI_B36_vs_Pooled_Sera_B36
- Old_vs_Young
- G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
- G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
- G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
- Control_Day_8_vs_Lactoferrin_Day_8
- G1_Klebsiella_pneumoniae_AJ218_RPMI_vs_G2_Klebsiella_pneumoniae_AJ218_Pooled_sera
- G1_Klebsiella_pneumoniae_AJ218_RPMI_vs_G2_Klebsiella_pneumoniae_AJ218_Pooled_sera
- G1_Pooled_Sera_Blood_4559_vs_G2_RPMI_Glucose_Blood_4559
- G1_Pooled_Sera_Blood_4559_vs_G2_RPMI_Glucose_Blood_4559
- G1_RPMI_modified_Blood_M1T1_5448_vs_G2_Pooled_sera_Blood_M1T1_5448
- G1_RPMI_modified_Blood_M1T1_5448_vs_G2_Pooled_sera_Blood_M1T1_5448
- WT_vs_WT_Aco
- G1_Exp1_0_hours_vs_G2_Exp1_6_hours
- G1_Frt_Ctrl_Day_6_vs_G3_Rasv12_Scrib_Day_6
- Wild_Type_vs_YQ2-gal
- Control_vs_Day_12
- Diet_D2_vs_Diet_D5
- 16_May_2012_vs_8_June_2012
- 16_May_2012_vs_8_June_2012
- Intracellular_vs_Extracellular
- Intracellular_vs_Extracellular
- Sham_vs_UIR
- 2:00 AM_Membrane_vs_2:00 AM_Net
- Control_vs_High
- Sham_vs_UIR
- 400ppm_0min_vs_800ppm_60min
- Control_14dpi_vs_Infected_14dpi
- Control_14dpi_vs_Infected_14dpi
- Iso31_Control_vs_Fumin_Homozygous_Sleep_Mutants
- ZH11_Mock_vs_ZH11_OsPep3
- Control_vs_Asymptomatic
- E1777_Intracellular_MidLog_vs_E1777_Intracellular_EarlyStationary
- Control_vs_OXPA_Treatment
- Control_vs_OXPA_Treatment
- Normal_control_no_tumor_vs_FH_deficient_RCC
- Hindgut_Control_vs_Lactobacillus_apis
- Embryo_S1_vs_Embryo_S4
- Control_vs_Basal_cold
- Untreated_vs_Antibiotic_Treated
- Untreated_vs_Antibiotic_Treated
- CC406_t2_vs_Stm6Glc4_t2
- Sham_vs_Heart_Failure_Sedentary
- Control_vs_Endometrial_Cancer
- Unfermented_vs_Fermented
- G1_Control_vs_G2_Arginine_Addition
- Sham_vs_Radiofrequency
- Glu_BW25113_vs_Pyr_BW25113
- Ziyun_No.1_0h_vs_Ziyun_No.1_96h
- Wild_type_vs_Knock_out
- Wild_Type_vs_Gene_Knockout
- Normal_vs_Neural_Tube_Defect
- Normal_vs_Neural_Tube_Defect
- Sham_vs_HIBD
- Control_vs_ZYP_High_Dose
- Dc-N_vs_Dc-HS
- Dcs_N_vs_Dcs_HS
- Male_19_days_vs_Male_1_day
- MCF-7_WT_vs_MCF-7_PKM2_KO
- Normal_Diet_vs_High-fat_Diet
- Normal_Diet_vs_High-fat_Diet
- Normal_Diet_vs_High-fat_Diet
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- Blood_10h_vs_Blood_58h
- DNA-PK_KO_UUO_vs_DNA-PK_KO_Control
- WT_vs_sll0404.ko
- Control_0h_vs_GABA_0h
- Control_Vehicle_vs_FSCN1_Knockout_Vehicle
- Control_vs_Fermented_Mulberry_Leaves
- Plasma_0h_vs_Plasma_48h
- MC-producing_Exponential_vs_MC-free_Exponential
- MC-producing_Exponential_vs_MC-free_Exponential
- Control_vs_Lactic_Acid
- wild_type_vs_patA_deletion
- 0_min_vs_60_min
- Uninfected_1h_vs_Anaplasma_phagocytophilum_1h
- Control_vs_BP3_Low_Concentration
- Yellow_Skin_vs_Green_Skin
- G1_Infected_Treated_vs_G2_Infected_Untreated
- ASD_Fecal_vs_TD_Fecal
- Arginine_Replenished_Ctrl_vs_Arginine_Starved_48h
- SAR-S_vs_SAR-R
- SAR-R_vs_SAR-S
- JURKAT_Control_vs_JURKAT_Treatment
- WT_vs_ErbB2_KI
- G1_Untreated_Control_vs_G2_2DG
- Human_Blood_vs_Human_Plasma
- Human_Blood_vs_Human_Plasma
- Human_Blood_vs_Human_Plasma
- Inbreeding_Growth_Chamber_0_day_vs_Inbreeding_Growth_Chamber_92_day
- Blood_vs_Plasma
- Blood_vs_Plasma