FSCN1 as a new druggable target in adrenocortical carcinoma

Study details

Source ID

https://identifiers.org/metabolights:MTBLS6402

Title

FSCN1 as a new druggable target in adrenocortical carcinoma

Summary

FSCN1 as a target in ACC treatment.

Observation

Effects of FSCN1 inactivation on ACC cell invasion.

Findings

FSCN1 inactivation reduces ACC cell invasion and metastasis.

Disease terms

ACC cancer, ACC, adrenocortical carcinoma, metastases, endocrine malignancy, Adrenocortical carcinoma

Gene terms

FSCN1, fascin, Rac, SF-1, VAV2, Steroidogenic Factor-1, beta-catenin

Chemical terms

—

Organisms

zebrafish, patients

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS6402.

{
  "@type": "Dataset",
  "go_id": [
    "https://identifiers.org/GO:0005737",
    "https://identifiers.org/GO:0007155"
  ],
  "go_kw": [
    "cytoplasm",
    "cell adhesion"
  ],
  "integmet_study": "MTBLS6402",
  "mesh_disease_id": [
    "https://identifiers.org/mesh:D000306",
    "https://identifiers.org/mesh:D018268",
    "https://identifiers.org/mesh:D009362",
    "https://identifiers.org/mesh:D004700"
  ],
  "mesh_disease_pubtator_kw": [
    "ACC cancer",
    "ACC",
    "adrenocortical carcinoma",
    "metastases",
    "endocrine malignancy",
    "Adrenocortical carcinoma"
  ],
  "mesh_gene_id": [
    "https://identifiers.org/ncbigene:6624",
    "https://identifiers.org/ncbigene:207",
    "https://identifiers.org/ncbigene:2516",
    "https://identifiers.org/ncbigene:7410",
    "https://identifiers.org/ncbigene:1499"
  ],
  "mesh_gene_pubtator_kw": [
    "FSCN1",
    "fascin",
    "Rac",
    "SF-1",
    "VAV2",
    "Steroidogenic Factor-1",
    "beta-catenin"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:7955",
    "https://identifiers.org/taxonomy:9606"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "zebrafish",
    "patients"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS6402",
  "study_findings": "FSCN1 inactivation reduces ACC cell invasion and metastasis.",
  "study_observation": "Effects of FSCN1 inactivation on ACC cell invasion.",
  "study_summary": "FSCN1 as a target in ACC treatment.",
  "study_title_original": "FSCN1 as a new druggable target in adrenocortical carcinoma"
}