Metabolomics dataset of PPAR-pan treated rat liver (acyl-carnitine and aqueous metabolite assays)

Study details

Source ID

https://identifiers.org/metabolights:MTBLS303

Title

Metabolomics dataset of PPAR-pan treated rat liver (acyl-carnitine and aqueous metabolite assays)

Summary

Metabolomics of PPAR-pan treated rat liver.

Observation

Small molecule changes in rat liver using LC-MS.

Findings

PPAR-pan activation induces hepatic oxidative stress and lipidomic remodelling.

Disease terms

metabolic diseases, inflammatory, type 2 diabetes, liver enlargement

Gene terms

PPAR, PPARalpha, gamma and delta, PPAR-alpha, -gamma, and -delta

Chemical terms

eicosanoid, adenosyl-methionine, lipid, PGB2, phospholipid, triacylglycerol, fatty-acid, fatty acid, free fatty acid, lipids, carnitines, fatty acids, eicosanoids, n-3 fatty acids

Organisms

rat, rats

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS303.

{
  "@type": "Dataset",
  "integmet_study": "MTBLS303",
  "mesh_chemical_id": [
    "https://identifiers.org/mesh:D015777",
    "https://identifiers.org/mesh:D012436",
    "https://identifiers.org/mesh:D008055",
    "https://identifiers.org/mesh:C042026",
    "https://identifiers.org/mesh:D010743",
    "https://identifiers.org/mesh:D014280",
    "https://identifiers.org/mesh:D005227",
    "https://identifiers.org/mesh:D005230",
    "https://identifiers.org/mesh:D002331",
    "https://identifiers.org/mesh:D015525"
  ],
  "mesh_chemical_pubtator_kw": [
    "eicosanoid",
    "adenosyl-methionine",
    "lipid",
    "PGB2",
    "phospholipid",
    "triacylglycerol",
    "fatty-acid",
    "fatty acid",
    "free fatty acid",
    "lipids",
    "carnitines",
    "fatty acids",
    "eicosanoids",
    "n-3 fatty acids"
  ],
  "mesh_disease_id": [
    "https://identifiers.org/mesh:D008659",
    "https://identifiers.org/mesh:D007249",
    "https://identifiers.org/mesh:D003924",
    "https://identifiers.org/mesh:D006529"
  ],
  "mesh_disease_pubtator_kw": [
    "metabolic diseases",
    "inflammatory",
    "type 2 diabetes",
    "liver enlargement"
  ],
  "mesh_gene_id": [
    "https://identifiers.org/ncbigene:25747",
    "https://identifiers.org/ncbigene:25747;25664"
  ],
  "mesh_gene_pubtator_kw": [
    "PPAR",
    "PPARalpha, gamma and delta",
    "PPAR-alpha, -gamma, and -delta"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:10116"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "rat",
    "rats"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS303",
  "study_findings": "PPAR-pan activation induces hepatic oxidative stress and lipidomic remodelling.",
  "study_observation": "Small molecule changes in rat liver using LC-MS.",
  "study_summary": "Metabolomics of PPAR-pan treated rat liver.",
  "study_title_original": "Metabolomics dataset of PPAR-pan treated rat liver (acyl-carnitine and aqueous metabolite assays)"
}