Diff Profiles › MTBLS106_0001_00000001

rps2_wildtype_vs_rps2_A226Y

rps2-wildtype vs rps2-A226Y

p-value ≤ 0.05 33 significant 2025-09-26 00:00:00 Study: MTBLS106
482 Total Features
33 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS106_0001_00000001
Linked study
MTBLS106 — Biological effect of chronic mistranslation in mammalian cells
Comparison
rps2-wildtype vs rps2-A226Y
Group A
Wild-type HEK-293 cells expressing normal RPS2 protein.. Serves as the reference group to assess the effects of the A226Y mutation.
Group B
HEK-293 cells expressing mutant RPS2 protein with A226Y mutation.. Allows for the investigation of the effects of the A226Y mutation on cellular processes.
Total features tested
482
Significant features
33
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
BOPGDPNILDQYTO-NNYOXOHSSA-N 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE up 1e+06 0.000183
UYVZIWWBJMYRCD-ZMHDXICWSA-J isovaleryl-coenzyme A(4−) up 1e+06 0.00381
NBAKTGXDIBVZOO-UHFFFAOYSA-N 5,6-Dihydro-5-methyluracil down 1e-06 0.00531
HAEVNYBCYZZDFL-UHFFFAOYSA-N 3-[(3-carboxypropanoyl)oxy]-4-(trimethylammonio)butanoate down 0.1522 0.000352
ARPVSMCNIDAQBO-YUMQZZPRSA-N <em>N</em>-<small>L</small>-glutaminyl-<small>L</small>-leucine down 0.1602 0.0177
HSQGMTRYSIHDAC-BQBZGAKWSA-N L-A down 0.1007 0.0456
IGQBPDJNUXPEMT-UHFFFAOYSA-N 3-methylbutyrylcarnitine down 0.3219 0.00222
AWUHAZDZHNWQAG-GFCCVEGCSA-O — down 0.3168 0.00656
GWHCXVQVJPWHRF-KTKRTIGZSA-M (<i>Z</i>)-tetracos-15-enoate down 0.3031 0.00794
CAHKINHBCWCHCF-UHFFFAOYSA-N <em>N</em>-acetyl-<small>D</small><small>L</small>-tyrosine up 3.589 0.0145