Absence of tmRNA increases the persistence to cefotaxime by upregulating the metabolites GlcNAc in Aeromonas veronii

Study details

Source ID

https://identifiers.org/metabolights:MTBLS1191

Title

Absence of tmRNA increases the persistence to cefotaxime by upregulating the metabolites GlcNAc in Aeromonas veronii

Summary

tmRNA absence increases cefotaxime persistence in Aeromonas veronii.

Observation

Absence of tmRNA in Aeromonas veronii.

Findings

tmRNA absence upregulates GlcNAc, increasing cefotaxime persistence.

Disease terms

infections

Gene terms

ssrA

Chemical terms

NaCl, GlcNAc, cefotaxime, Cefotaxime, beta-lactams, beta-lactam

Organisms

Aeromonas veronii, A. veronii, human

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS1191.

{
  "@type": "Dataset",
  "go_id": [
    "https://identifiers.org/GO:0008152",
    "https://identifiers.org/GO:0016049",
    "https://identifiers.org/GO:0006412",
    "https://identifiers.org/GO:0006351",
    "https://identifiers.org/GO:0009252"
  ],
  "go_kw": [
    "metabolism",
    "cell growth",
    "translation",
    "transcription",
    "peptidoglycan biosynthesis"
  ],
  "integmet_study": "MTBLS1191",
  "mesh_chemical_id": [
    "https://identifiers.org/mesh:D012965",
    "https://identifiers.org/mesh:D000117",
    "https://identifiers.org/mesh:D002439",
    "https://identifiers.org/mesh:D047090"
  ],
  "mesh_chemical_pubtator_kw": [
    "NaCl",
    "GlcNAc",
    "cefotaxime",
    "Cefotaxime",
    "beta-lactams",
    "beta-lactam"
  ],
  "mesh_disease_id": [
    "https://identifiers.org/mesh:D007239"
  ],
  "mesh_disease_pubtator_kw": [
    "infections"
  ],
  "mesh_gene_id": [
    "https://identifiers.org/ncbigene:28678094"
  ],
  "mesh_gene_pubtator_kw": [
    "ssrA"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:654",
    "https://identifiers.org/taxonomy:9606"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "Aeromonas veronii",
    "A. veronii",
    "human"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS1191",
  "study_findings": "tmRNA absence upregulates GlcNAc, increasing cefotaxime persistence.",
  "study_observation": "Absence of tmRNA in Aeromonas veronii.",
  "study_summary": "tmRNA absence increases cefotaxime persistence in Aeromonas veronii.",
  "study_title_original": "Absence of tmRNA increases the persistence to cefotaxime by upregulating the metabolites GlcNAc in Aeromonas veronii"
}