Diff Profiles › MTBLS795_0001_00000001

WT_vs_ErbB2_KI

WT vs ErbB2 KI

p-value ≤ 0.05 34 significant 2025-09-26 00:00:00 Study: MTBLS795
388 Total Features
34 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS795_0001_00000001
Linked study
MTBLS795 — Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency.
Comparison
WT vs ErbB2 KI
Group A
Wild-type control group. Serves as the reference point for all other genetically modified groups.
Group B
ErbB2 knock-in group. Used to study the effects of ErbB2 knock-in on cardiac function.
Total features tested
388
Significant features
34
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
ZSLZBFCDCINBPY-ZSJPKINUSA-N Acetyl-CoA down 0.4626 8.44e-05
LESXFEZIFXFIQR-LURJTMIESA-N Leucyl-Glycine down 0.402 0.0015
RFSUNEUAIZKAJO-ARQDHWQXSA-N beta-D-arabino-Hexulose down 0.2855 0.0109
STKYPAFSDFAEPH-LURJTMIESA-N Gly-<small>L</small>-Val down 0.5115 0.000266
XCTHZFGSVQBHBW-IUCAKERBSA-N VL down 0.3657 0.00538
SSISHJJTAXXQAX-ZETCQYMHSA-N (α<i>S</i>)-α-carboxy-2,3-dihydro-<em>N</em>,<em>N</em>,<em>N</em>-trimethyl-2-thioxo-1<em>H</em>-imidazole-4-ethanaminium inner salt down 0.4464 0.00173
IETVQHUKTKKBFF-UHFFFAOYSA-N 4-ethenylphenyl hydrogen sulfate down 0.5096 0.00084
GUBGYTABKSRVRQ-PICCSMPSSA-N Malzzucker down 0.2934 0.0207
LRCNOZRCYBNMEP-UHFFFAOYSA-N isobutyrylcarnitine up 2.222 0.00291
ATHGHQPFGPMSJY-UHFFFAOYSA-N N-(3-Aminopropyl)-1,4-butane-diamine down 0.5857 0.000301