Host autophagy mediates organ wasting and nutrient mobilization for tumor growth.

Study details

Source ID

https://identifiers.org/metabolights:MTBLS2771

Title

Host autophagy mediates organ wasting and nutrient mobilization for tumor growth.

Summary

Autophagy supports tumor growth via organ wasting.

Observation

Systemic organ wasting and nutrient mobilization in Drosophila melanogaster tumor model.

Findings

Host autophagy mediates organ wasting and nutrient mobilization for tumor growth.

Disease terms

organ wasting, wasting, muscle atrophy, tumors, loss, tumor, death, malignant tumor

Gene terms

RasV12, scrib

Chemical terms

sugars, Carbon 13

Organisms

Drosophila melanogaster

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS2771.

{
  "@type": "Dataset",
  "go_id": [
    "https://identifiers.org/GO:0014889",
    "https://identifiers.org/GO:0005764",
    "https://identifiers.org/GO:0006914"
  ],
  "go_kw": [
    "muscle atrophy",
    "lysosome",
    "autophagy"
  ],
  "integmet_study": "MTBLS2771",
  "mesh_chemical_id": [
    "https://identifiers.org/mesh:D000073893",
    "https://identifiers.org/mesh:C000615229"
  ],
  "mesh_chemical_pubtator_kw": [
    "sugars",
    "Carbon 13"
  ],
  "mesh_disease_id": [
    "https://identifiers.org/mesh:D000092124",
    "https://identifiers.org/mesh:D019282",
    "https://identifiers.org/mesh:D009133",
    "https://identifiers.org/mesh:D009369",
    "https://identifiers.org/mesh:D016388",
    "https://identifiers.org/mesh:D003643"
  ],
  "mesh_disease_pubtator_kw": [
    "organ wasting",
    "wasting",
    "muscle atrophy",
    "tumors",
    "loss",
    "tumor",
    "death",
    "malignant tumor"
  ],
  "mesh_gene_id": [
    "https://identifiers.org/ncbigene:41140",
    "https://identifiers.org/ncbigene:44448"
  ],
  "mesh_gene_pubtator_kw": [
    "RasV12",
    "scrib"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:7227"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "Drosophila melanogaster"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS2771",
  "study_findings": "Host autophagy mediates organ wasting and nutrient mobilization for tumor growth.",
  "study_observation": "Systemic organ wasting and nutrient mobilization in Drosophila melanogaster tumor model.",
  "study_summary": "Autophagy supports tumor growth via organ wasting.",
  "study_title_original": "Host autophagy mediates organ wasting and nutrient mobilization for tumor growth."
}