Bile acid is a significant host factor shaping the gut microbiome of diet induced obese mice (untargeted metabolome profile assay)

Study details

Source ID

https://identifiers.org/metabolights:MTBLS545

Title

Bile acid is a significant host factor shaping the gut microbiome of diet induced obese mice (untargeted metabolome profile assay)

Summary

Bile acids shape gut microbiome in obese mice.

Observation

Bile acids and gut microbiome interactions in diet-induced obese mice.

Findings

Bile acids significantly alter gut microbiota; potential therapeutic target for metabolic diseases.

Disease terms

metabolic diseases, obese, metabolic disorders, obesity

Gene terms

FXR

Chemical terms

Bile acid, BAs, bile acid, BA

Organisms

mice

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS545.

{
  "@type": "Dataset",
  "go_id": [
    "https://identifiers.org/GO:0065007",
    "https://identifiers.org/GO:0008152",
    "https://identifiers.org/GO:0005634"
  ],
  "go_kw": [
    "regulation",
    "metabolism",
    "nucleus"
  ],
  "integmet_study": "MTBLS545",
  "mesh_chemical_id": [
    "https://identifiers.org/mesh:D001647",
    "https://identifiers.org/mesh:D001464"
  ],
  "mesh_chemical_pubtator_kw": [
    "Bile acid",
    "BAs",
    "bile acid",
    "BA"
  ],
  "mesh_disease_id": [
    "https://identifiers.org/mesh:D008659",
    "https://identifiers.org/mesh:D009765"
  ],
  "mesh_disease_pubtator_kw": [
    "metabolic diseases",
    "obese",
    "metabolic disorders",
    "obesity"
  ],
  "mesh_gene_id": [
    "https://identifiers.org/ncbigene:20186"
  ],
  "mesh_gene_pubtator_kw": [
    "FXR"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:10090"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "mice"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS545",
  "study_findings": "Bile acids significantly alter gut microbiota; potential therapeutic target for metabolic diseases.",
  "study_observation": "Bile acids and gut microbiome interactions in diet-induced obese mice.",
  "study_summary": "Bile acids shape gut microbiome in obese mice.",
  "study_title_original": "Bile acid is a significant host factor shaping the gut microbiome of diet induced obese mice (untargeted metabolome profile assay)"
}