Diff Profiles › MTBLS545_0001_00000001

Normal_Diet_vs_High-fat_Diet

Normal_Diet vs High-fat_Diet

p-value ≤ 0.05 6 significant 2025-09-26 00:00:00 Study: MTBLS545
145 Total Features
6 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS545_0001_00000001
Linked study
MTBLS545 — Bile acid is a significant host factor shaping the gut microbiome of diet induced obese mice (untargeted metabolome profile assay)
Comparison
Normal_Diet vs High-fat_Diet
Group A
Mice fed with a normal diet.. Provides baseline data for comparison with high-fat diet samples.
Group B
Mice fed with a high-fat diet.. Allows for the assessment of the impact of a high-fat diet on gut microbiota and bile acid metabolism.
Total features tested
145
Significant features
6
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
FSYKKLYZXJSNPZ-UHFFFAOYSA-N L-sarcosine up 2.738 0.0238
PHOQVHQSTUBQQK-SQOUGZDYSA-N <small>D</small>-gluconic acid lactone down 0.3361 0.0408
BJHIKXHVCXFQLS-OTWZMJIISA-N (3<i>S</i>,4<i>R</i>,5<i>S</i>)-1,3,4,5,6-pentahydroxyhexan-2-one down 0.4125 0.0234
HEBKCHPVOIAQTA-IMJSIDKUSA-N L-lyxitol down 0.4976 0.0282
GUBGYTABKSRVRQ-XLOQQCSPSA-N LACTOSE down 0.4982 0.0311
ODBLHEXUDAPZAU-UHFFFAOYSA-N Isocitric acid down 0.6007 0.0387