{"comparisonGroups":["Normal_Diet","High-fat_Diet"],"dateCreated":"2025-09-26 00:00:00","display_title":"Mouse gut: normal diet vs high-fat diet","group_a_title":"Mice fed with a normal diet.. Provides baseline data for comparison with high-fat diet samples.","group_b_title":"Mice fed with a high-fat diet.. Allows for the assessment of the impact of a high-fat diet on gut microbiota and bile acid metabolism.","id":"MTBLS545_0001_00000001","pvalueThreshold":0.05,"ratioThresholdLower":"1/1.5","ratioThresholdUpper":1.5,"significantFeatures":6,"studyId":"MTBLS545","studyUrl":"http://integmet.org/study/MTBLS545","title":"Normal_Diet_vs_High-fat_Diet","topHits":[{"chebi_id":"15611","direction":"up","inn_name":"","iupac_name":"sarcosine","metabolite_id":"FSYKKLYZXJSNPZ-UHFFFAOYSA-N","pvalue":0.0237944280792536,"ratio":2.738067744418784,"synonym_name":"L-sarcosine"},{"chebi_id":"16217","direction":"down","inn_name":"","iupac_name":"(3<i>R</i>,4<i>S</i>,5<i>S</i>,6<i>R</i>)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-one","metabolite_id":"PHOQVHQSTUBQQK-SQOUGZDYSA-N","pvalue":0.0408495887288133,"ratio":0.336082159355553,"synonym_name":"<small>D</small>-gluconic acid lactone"},{"chebi_id":"13172","direction":"down","inn_name":"","iupac_name":"<em>keto</em>-<small>L</small>-sorbose","metabolite_id":"BJHIKXHVCXFQLS-OTWZMJIISA-N","pvalue":0.0233782048870268,"ratio":0.4124766570382858,"synonym_name":"(3<i>S</i>,4<i>R</i>,5<i>S</i>)-1,3,4,5,6-pentahydroxyhexan-2-one"},{"chebi_id":"18403","direction":"down","inn_name":"","iupac_name":"<small>L</small>-arabinitol","metabolite_id":"HEBKCHPVOIAQTA-IMJSIDKUSA-N","pvalue":0.0281867876635673,"ratio":0.4976421636615812,"synonym_name":"L-lyxitol"},{"chebi_id":"36219","direction":"down","inn_name":"","iupac_name":"\u03b2-<small>D</small>-galactopyranosyl-(1\u21924)-\u03b1-<small>D</small>-glucopyranose","metabolite_id":"GUBGYTABKSRVRQ-XLOQQCSPSA-N","pvalue":0.0310702540527316,"ratio":0.4981628540950574,"synonym_name":"LACTOSE"},{"chebi_id":"30887","direction":"down","inn_name":"","iupac_name":"1-hydroxypropane-1,2,3-tricarboxylic acid","metabolite_id":"ODBLHEXUDAPZAU-UHFFFAOYSA-N","pvalue":0.0386557493545183,"ratio":0.6006655574043261,"synonym_name":"Isocitric acid"}],"totalFeatures":145}