Absence of tmRNA Increases the Persistence to Cefotaxime and the Intercellular Accumulation of Metabolite GlcNAc in <i>Aeromonas veronii</i>.

Study details

Source ID

https://identifiers.org/metabolights:MTBLS1182

Title

Absence of tmRNA Increases the Persistence to Cefotaxime and the Intercellular Accumulation of Metabolite GlcNAc in <i>Aeromonas veronii</i>.

Summary

tmRNA absence increases cefotaxime persistence in A. veronii.

Observation

Absence of tmRNA in Aeromonas veronii.

Findings

Increased cefotaxime persistence and GlcNAc accumulation in tmRNA deletion strains.

Disease terms

infections

Gene terms

ssrA

Chemical terms

NaCl, GlcNAc, cefotaxime, Cefotaxime, beta-lactams, beta-lactam

Organisms

Aeromonas veronii, A. veronii, human

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS1182.

{
  "@type": "Dataset",
  "go_id": [
    "https://identifiers.org/GO:0006970",
    "https://identifiers.org/GO:0010287",
    "https://identifiers.org/GO:0009058",
    "https://identifiers.org/GO:0006412",
    "https://identifiers.org/GO:0009273"
  ],
  "go_kw": [
    "osmotic response",
    "peptidoglycan (PG) biosynthesis",
    "biosynthesis",
    "protein synthesis",
    "cell wall formation"
  ],
  "integmet_study": "MTBLS1182",
  "mesh_chemical_id": [
    "https://identifiers.org/mesh:D012965",
    "https://identifiers.org/mesh:D000117",
    "https://identifiers.org/mesh:D002439",
    "https://identifiers.org/mesh:D047090"
  ],
  "mesh_chemical_pubtator_kw": [
    "NaCl",
    "GlcNAc",
    "cefotaxime",
    "Cefotaxime",
    "beta-lactams",
    "beta-lactam"
  ],
  "mesh_disease_id": [
    "https://identifiers.org/mesh:D007239"
  ],
  "mesh_disease_pubtator_kw": [
    "infections"
  ],
  "mesh_gene_id": [
    "https://identifiers.org/ncbigene:28678094"
  ],
  "mesh_gene_pubtator_kw": [
    "ssrA"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:654",
    "https://identifiers.org/taxonomy:9606"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "Aeromonas veronii",
    "A. veronii",
    "human"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS1182",
  "study_findings": "Increased cefotaxime persistence and GlcNAc accumulation in tmRNA deletion strains.",
  "study_observation": "Absence of tmRNA in Aeromonas veronii.",
  "study_summary": "tmRNA absence increases cefotaxime persistence in A. veronii.",
  "study_title_original": "Absence of tmRNA Increases the Persistence to Cefotaxime and the Intercellular Accumulation of Metabolite GlcNAc in \u003ci\u003eAeromonas veronii\u003c/i\u003e."
}