Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Brain tissue metabolomics)

Study details

Source ID

https://identifiers.org/metabolights:MTBLS4894

Title

Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Brain tissue metabolomics)

Summary

Sodium butyrate affects HIBD via gut microbiota.

Observation

Neonatal HIBD rats' gut microbiota and brain SCFAs levels.

Findings

Sodium butyrate ameliorates HIBD by altering gut microbiota and histone crotonylation.

Disease terms

neural tube defects, NTDs

Gene terms

—

Chemical terms

lipid, unsaturated fatty acids, folic acid, glycerophospholipid, folate

Organisms

—

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS4894.

{
  "@type": "Dataset",
  "integmet_study": "MTBLS4894",
  "mesh_chemical_id": [
    "https://identifiers.org/mesh:D008055",
    "https://identifiers.org/mesh:D005231",
    "https://identifiers.org/mesh:D005492",
    "https://identifiers.org/mesh:D020404"
  ],
  "mesh_chemical_pubtator_kw": [
    "lipid",
    "unsaturated fatty acids",
    "folic acid",
    "glycerophospholipid",
    "folate"
  ],
  "mesh_disease_id": [
    "https://identifiers.org/mesh:D009436"
  ],
  "mesh_disease_pubtator_kw": [
    "neural tube defects",
    "NTDs"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS4894",
  "study_findings": "Sodium butyrate ameliorates HIBD by altering gut microbiota and histone crotonylation.",
  "study_observation": "Neonatal HIBD rats\u0027 gut microbiota and brain SCFAs levels.",
  "study_summary": "Sodium butyrate affects HIBD via gut microbiota.",
  "study_title_original": "Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Brain tissue metabolomics)"
}