Diff Profiles › MTBLS739_0001_00000001

Low_Shear_Stress_vs_High_Shear_Stress

Low_Shear_Stress vs High_Shear_Stress

p-value ≤ 0.05 27 significant 2025-09-26 00:00:00 Study: MTBLS739
104 Total Features
27 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS739_0001_00000001
Linked study
MTBLS739 — Integrated Proteomics and Metabolomics Analysis Reveals Differential Lipid Metabolism in HUVEC under high and low shear stress
Comparison
Low_Shear_Stress vs High_Shear_Stress
Group A
Endothelial cells under low shear stress conditions.. Represents the condition associated with upregulation of inflammatory, adhesion, and cellular permeability molecules.
Group B
Endothelial cells under high shear stress conditions.. Represents the condition associated with increased expression of protective and anti-inflammatory factors.
Total features tested
104
Significant features
27
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
QNAYBMKLOCPYGJ-REOHCLBHSA-N (2<i>S</i>)-2-aminopropanoic acid up 1e+06 0.00047
BJHIKXHVCXFQLS-OTWZMJIISA-N (3<i>S</i>,4<i>R</i>,5<i>S</i>)-1,3,4,5,6-pentahydroxyhexan-2-one up 1e+06 0.00137
JSSKAZULTFHXBH-UHFFFAOYSA-N 3-tetradecoxypropane-1,2-diol down 1e-06 0.00777
DCXYFEDJOCDNAF-REOHCLBHSA-N (2<i>S</i>)-2-ammonio-3-carbamoylpropanoate up 1e+06 0.0105
KDXKERNSBIXSRK-YFKPBYRVSA-N L-Lysine up 1e+06 0.0196
CHTHALBTIRVDBM-UHFFFAOYSA-N Furane-alpha,alpha'-dicarboxylic acid up 1e+06 0.0227
VEYYWZRYIYDQJM-ZETCQYMHSA-N <em>N</em><small><sup>α</small></sup>-acetyl-<small>L</small>-lysine up 1e+06 0.0322
WKRBKYFIJPGYQC-UHFFFAOYSA-N 3-methyl-2-pentenedioic acid up 1e+06 0.0415
AFNUZVCFKQUDBJ-MDMQIMBFSA-N 6-deoxy-α-L-mannofuranose down 1e-06 0.0467
IERHLVCPSMICTF-XVFCMESISA-N Cytidine-5'-monophosphate down 1e-06 0.0468