{"comparisonGroups":["Low_Shear_Stress","High_Shear_Stress"],"dateCreated":"2025-09-26 00:00:00","display_title":"Endothelial cells: low vs high shear stress","group_a_title":"Endothelial cells under low shear stress conditions.. Represents the condition associated with upregulation of inflammatory, adhesion, and cellular permeability molecules.","group_b_title":"Endothelial cells under high shear stress conditions.. Represents the condition associated with increased expression of protective and anti-inflammatory factors.","id":"MTBLS739_0001_00000001","pvalueThreshold":0.05,"ratioThresholdLower":"1/1.5","ratioThresholdUpper":1.5,"significantFeatures":27,"studyId":"MTBLS739","studyUrl":"http://integmet.org/study/MTBLS739","title":"Low_Shear_Stress_vs_High_Shear_Stress","topHits":[{"chebi_id":"16977","direction":"up","inn_name":"","iupac_name":"<small>L</small>-alanine","metabolite_id":"QNAYBMKLOCPYGJ-REOHCLBHSA-N","pvalue":0.0004697074802926,"ratio":1000000.0,"synonym_name":"(2<i>S</i>)-2-aminopropanoic acid"},{"chebi_id":"13172","direction":"up","inn_name":"","iupac_name":"<em>keto</em>-<small>L</small>-sorbose","metabolite_id":"BJHIKXHVCXFQLS-OTWZMJIISA-N","pvalue":0.0013717258753698,"ratio":1000000.0,"synonym_name":"(3<i>S</i>,4<i>R</i>,5<i>S</i>)-1,3,4,5,6-pentahydroxyhexan-2-one"},{"chebi_id":"144328","direction":"down","inn_name":"","iupac_name":"3-tetradecoxypropane-1,2-diol","metabolite_id":"JSSKAZULTFHXBH-UHFFFAOYSA-N","pvalue":0.0077719826169205,"ratio":1e-06,"synonym_name":""},{"chebi_id":"58048","direction":"up","inn_name":"","iupac_name":"(2<i>S</i>)-4-amino-2-azaniumyl-4-oxobutanoate","metabolite_id":"DCXYFEDJOCDNAF-REOHCLBHSA-N","pvalue":0.0105383808058681,"ratio":1000000.0,"synonym_name":"(2<i>S</i>)-2-ammonio-3-carbamoylpropanoate"},{"chebi_id":"18019","direction":"up","inn_name":"lysine","iupac_name":"(2<i>S</i>)-2,6-diaminohexanoic acid","metabolite_id":"KDXKERNSBIXSRK-YFKPBYRVSA-N","pvalue":0.0195917318270082,"ratio":1000000.0,"synonym_name":"L-Lysine"},{"chebi_id":"84212","direction":"up","inn_name":"","iupac_name":"furan-2,5-dicarboxylic acid","metabolite_id":"CHTHALBTIRVDBM-UHFFFAOYSA-N","pvalue":0.0226683367419739,"ratio":1000000.0,"synonym_name":"Furane-alpha,alpha'-dicarboxylic acid"},{"chebi_id":"35704","direction":"up","inn_name":"","iupac_name":"<em>N</em><small><sup>2</small></sup>-acetyl-<small>L</small>-lysine","metabolite_id":"VEYYWZRYIYDQJM-ZETCQYMHSA-N","pvalue":0.0321613354089232,"ratio":1000000.0,"synonym_name":"<em>N</em><small><sup>\u03b1</small></sup>-acetyl-<small>L</small>-lysine"},{"chebi_id":"144330","direction":"up","inn_name":"","iupac_name":"3-methylpent-2-enedioic acid","metabolite_id":"WKRBKYFIJPGYQC-UHFFFAOYSA-N","pvalue":0.0414719535360103,"ratio":1000000.0,"synonym_name":"3-methyl-2-pentenedioic acid"},{"chebi_id":"75892","direction":"down","inn_name":"","iupac_name":"6-deoxy-\u03b1-<small>L</small>-mannofuranose","metabolite_id":"AFNUZVCFKQUDBJ-MDMQIMBFSA-N","pvalue":0.046688742711088,"ratio":1e-06,"synonym_name":""},{"chebi_id":"17361","direction":"down","inn_name":"","iupac_name":"5'-cytidylic acid","metabolite_id":"IERHLVCPSMICTF-XVFCMESISA-N","pvalue":0.0467652729307513,"ratio":1e-06,"synonym_name":"Cytidine-5'-monophosphate"}],"totalFeatures":104}